Detailed Information on Publication Record
2007
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
PŘIKRYL, Radovan, Simona SKOTÁKOVÁ, Tomáš KAŠPÁREK, Eva ČEŠKOVÁ, Hana KUČEROVÁ et. al.Basic information
Original name
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
Name in Czech
Ovlivnění negativních příznaků schizofrenie prostřednictvím repetitivní transkraniální magnetické stimulace: kazuistické sdělení
Name (in English)
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
Authors
PŘIKRYL, Radovan (203 Czech Republic, guarantor), Simona SKOTÁKOVÁ (203 Czech Republic), Tomáš KAŠPÁREK (203 Czech Republic), Eva ČEŠKOVÁ (203 Czech Republic), Hana KUČEROVÁ (203 Czech Republic) and Libor USTOHAL (203 Czech Republic)
Edition
Acta Neuropsychiatrica, Australia, Blackwell Publishing, 2007, 0924-2708
Other information
Language
Czech
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.206
RIV identification code
RIV/00216224:14110/07:00019061
Organization unit
Faculty of Medicine
UT WoS
000245231200008
Keywords in English
negative symptoms; schizophrenia; rTMS
Tags
Tags
International impact, Reviewed
Změněno: 19/6/2009 14:02, prof. MUDr. Eva Češková, CSc.
V originále
Background: The present trial was designed to investigate the influence of repetitive transcranial magnetic stimulation (rTMS) on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
In English
Background: The present trial was designed to investigate the influence of repetitive transcranial magnetic stimulation (rTMS) on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
Links
| MSM0021622404, plan (intention) |
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| NR7986, research and development project |
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