Detailed Information on Publication Record
2006
Decrease of humic acids AhR mediated activity after irradiation
BITTNER, Michal, Klára HILSCHEROVÁ, Jaroslav JANOŠEK, Luděk BLÁHA, John, Paul GIESY et. al.Basic information
Original name
Decrease of humic acids AhR mediated activity after irradiation
Name in Czech
Snížení AhRzprostředkované aktivity huminových látek po ozáření
Authors
BITTNER, Michal (203 Czech Republic, guarantor, belonging to the institution), Klára HILSCHEROVÁ (203 Czech Republic, belonging to the institution), Jaroslav JANOŠEK (203 Czech Republic, belonging to the institution), Luděk BLÁHA (203 Czech Republic, belonging to the institution), John, Paul GIESY (840 United States of America) and Ivan HOLOUBEK (203 Czech Republic, belonging to the institution)
Edition
Book of abstracts - International Conference on Ecotoxicology: Trends and Perspectives, 2006
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30304 Public and environmental health
Country of publisher
Poland
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/06:00016467
Organization unit
Faculty of Science
Keywords in English
Humic substances; Ah Receptor; Irradiation; Toxicity
Tags
International impact, Reviewed
Změněno: 27/4/2011 12:37, prof. RNDr. Luděk Bláha, Ph.D.
V originále
The reporter gene in vitro bioassay with H4IIEluc cells was used for determination of AhR mediated activity of HA. H4IIE-luc are stably transfected hepatoma cells with a luciferase reporter gene that is activated via AhR. Irradiation of five different aqueous HA samples were carried out in pyrex tubes using low pressure mercury lamp. Concentrations of irradiated HA samples were 50 mg/L, and irradiation times were from 0 to 37 hours. In this contribution, we summarize our new findings on alteration of AhR mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation induced decrease in AhR-mediated activity of dissolved HS is discussed.
In Czech
Huminové látky jsou velmi důležitou součástí prostředí. Tato studie poukázala na jejich možné specifické účinky in vitro a také charakterizovala změnu těchto účinku při ozáření.
Links
| GP525/05/P160, research and development project |
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| MSM0021622412, plan (intention) |
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