Detailed Information on Publication Record
2007
Homocysteine, folate and vitamin B12 in seminal plasma
CRHA, Igor, Jitka MELOUNOVÁ, Michaela KRÁLÍKOVÁ, Jaroslava TALLOVÁ, Jiří JARKOVSKÝ et. al.Basic information
Original name
Homocysteine, folate and vitamin B12 in seminal plasma
Name in Czech
Homocystein, folát a vitamin B12 v seminální plasmě
Authors
CRHA, Igor (203 Czech Republic, guarantor, belonging to the institution), Jitka MELOUNOVÁ (203 Czech Republic, belonging to the institution), Michaela KRÁLÍKOVÁ (203 Czech Republic, belonging to the institution), Jaroslava TALLOVÁ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Jana ŽÁKOVÁ (203 Czech Republic, belonging to the institution) and Pavel VENTRUBA (203 Czech Republic, belonging to the institution)
Edition
2007
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30214 Obstetrics and gynaecology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/07:00041490
Organization unit
Faculty of Medicine
UT WoS
000255322200543
Keywords in English
homocysteine; folate; reproduction; seminal plasma
Tags
Tags
International impact, Reviewed
Změněno: 29/4/2011 11:03, prof. RNDr. Luděk Bláha, Ph.D.
V originále
Elevated plasma homocysteine is an independent risk factor for the development of many pathological states, but at present, there is only little information about its concentration in seminal fluid. It is also well known that folate plays an important role in the reproduction and that the treatment with folate antagonists impairs the reproductive functions in men. A previous study found that low seminal plasma folate concentrations are associated with low sperm density and sperm count and that folate concentrations in the seminal fluid correlate with blood plasma folate and homocysteine. The homocysteine, vitamin B12 and folate concentrations were significantly higher in men with normospermia than in men with azoospermia and oligoasthenospermia. Negative correlation between folate and homocystein in normospermia group was found. Low levels of homocysteine in the group with azoospermia may indicate decreased metabolic activity in the testes of these men.
In Czech
Koncentrace homocysteinu, vitaminu B12 a folátu byly signifikantně vyšší u mužů s normospermií než u mužů s azoospermií a oligoasthenospermií. Byla prokázána negativní korelace mezi folátem a homocysteinem u mužů s normoseprmií. Nízké hladiny homocysteinu u mužů s azoospermií svědčí pro sníženou metabolickou aktivitu testikulární tkáně.
Links
| MSM0021622412, plan (intention) |
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