Slovácko is a unique region in the southeast Moravia. This originally ethnographic region regains its significance in recent times, especially in a context of a regional and cultural development in this area. Administratively the main part of Slovácko region consists of the Hodonín and Uherské Hradiště districts. These are significantly different in a labour market conditions, as a rate of unemployment in Hodonín district is one of the highest in the Czech republic. The authors of this paper are trying to evaluate regional (economical) effects of each individual centres (as well as a whole region) on a surrounding area using Reilly's model, with regards to different labour market conditions.