VÁLEK, Vlastimil, Petr KYSELA, Zdeněk KALA, Igor KISS, Jiří TOMÁŠEK and Jiří PETERA. Brachytherapy and percutaneous stenting in the treatment of cholangiocarcinoma: a prospective randomised study. European journal of radiology. Ireland: Elsevier Science Ireland Ltd, 2007, vol. 62, No 2, p. 175-9, 5 pp. ISSN 0720-048X.
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Basic information
Original name Brachytherapy and percutaneous stenting in the treatment of cholangiocarcinoma: a prospective randomised study.
Name in Czech Brachyterapie a perkutánní stenting v léčbě cholangiokarcinomu. prospektivní studie
Authors VÁLEK, Vlastimil (203 Czech Republic, guarantor), Petr KYSELA (203 Czech Republic), Zdeněk KALA (203 Czech Republic), Igor KISS (203 Czech Republic), Jiří TOMÁŠEK (203 Czech Republic) and Jiří PETERA (203 Czech Republic).
Edition European journal of radiology, Ireland, Elsevier Science Ireland Ltd, 2007, 0720-048X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.915
RIV identification code RIV/00216224:14110/07:00032290
Organization unit Faculty of Medicine
UT WoS 000246613700006
Keywords in English brachytherapy;biliary stent;cholangiocarcinoma; treatment
Tags biliary stent, brachytherapy, cholangiocarcinoma, treatment
Tags International impact
Changed by Changed by: Ing. Blanka Přikrylová, učo 71313. Changed: 12/4/2010 22:52.
Abstract
PURPOSE: To evaluate the effect of radiation therapy including intraluminal brachyterapy with iridium-192 on survival of patients with malignant biliary strictures (cholangiocarcinoma, histologically improved) treated with metallic stent in a prospective randomised study. METHOD AND MATERIALS: In the prospective randomised study, 21 patients with cholangiocarcinoma were treated with implantation of percutaneous stents followed with intraluminal Ir-192 brachytherapy (mean dose 30 Gy) and external radiotherapy (mean dose 50 Gy) and 21 patients were treated only with stents insertion. We did not find any statistically significant differences in age and tumor localization between these two groups of patients. RESULTS: All the patients died. In the group of patients treated with brachytherapy and with stent implantation, the mean survival time was 387.9 days. In the group of patients treated only with stent insertion the mean survival was 298 days. In effort to eliminate possible effect of external radiotherapy we treated the control group of eight patients with cholangiocarcinoma by stent insertion and brachyterapy only. CONCLUSION: Our results show that combined radiation therapy could extend the survival in the patients with cholangiocarcinoma obstruction.
Abstract (in Czech)
Prospektivní randomizovaná studie prokazující přízivý efekt kombinace lokální endoluminální radioterapie s implantaci kovového stentu u pacientů s cholengiocelulárním karcinomem na přežití.
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