BRABEC, Kamil and Vojtěch MORNSTEIN. Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal. Central European Journal of Biology. Springer Versita, 2007, vol. 2, No 2, p. 213-221. ISSN 1895-104X.
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Basic information
Original name Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal
Name in Czech Detekce ultrazvukové kavitace založená na nízkofrekvenční analýze akustického signálu
Authors BRABEC, Kamil (203 Czech Republic, guarantor) and Vojtěch MORNSTEIN (203 Czech Republic).
Edition Central European Journal of Biology, Springer Versita, 2007, 1895-104X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10610 Biophysics
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.250
RIV identification code RIV/00216224:14110/07:00032317
Organization unit Faculty of Medicine
UT WoS 000246984400005
Keywords in English ultrasound; ultrasonic cavitation; echocontrast agent; microbubbles; low-frequency analysis; cavitation threshold
Tags cavitation threshold, echocontrast agent, low-frequency analysis, microbubbles, ultrasonic cavitation, ultrasound
Changed by Changed by: prof. RNDr. Vojtěch Mornstein, CSc., učo 2001. Changed: 15/3/2010 20:25.
Abstract
The acoustic cavitation phenomenon constitutes a potential hazard in ultrasound diagnostics and therapy so that early and effective detection of cavitation is of great interest. However, cavitation might even bring a higher risk especially when an echocontrast agent based on microbubbles is used. The major goal of the present work was to develop a cavitation detection method based on increased level of cavitation noise in the range of low frequencies ( about 1 Hz). This method was applied in vitro using a model of body fluid containing a model echocontrast agent, such as 5% solution of lyophilized egg albumin, which was sonicated by ultrasound disintegrator. Ultrasound signal evokes cavitation in microbubble suspension accompanied by a certain level of cavitation acoustic noise. The level of noise voltage increased in the frequency range of 0.1 to 2 Hz in the presence of cavitation. Hence, this method makes it possible to determine the value of cavitation threshold. In addition, we examined how the cavitation threshold is affected by temperature and viscosity. It was found that the cavitation threshold decreased with growing temperature while it increased with growing viscosity.
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