J 2007

Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal

BRABEC, Kamil and Vojtěch MORNSTEIN

Basic information

Original name

Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal

Name in Czech

Detekce ultrazvukové kavitace založená na nízkofrekvenční analýze akustického signálu

Authors

BRABEC, Kamil (203 Czech Republic, guarantor) and Vojtěch MORNSTEIN (203 Czech Republic)

Edition

Central European Journal of Biology, Springer Versita, 2007, 1895-104X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10610 Biophysics

Country of publisher

Poland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.250

RIV identification code

RIV/00216224:14110/07:00032317

Organization unit

Faculty of Medicine

UT WoS

000246984400005

Keywords in English

ultrasound; ultrasonic cavitation; echocontrast agent; microbubbles; low-frequency analysis; cavitation threshold

Tags

Změněno: 15/3/2010 20:25, prof. RNDr. Vojtěch Mornstein, CSc.

Abstract

V originále

The acoustic cavitation phenomenon constitutes a potential hazard in ultrasound diagnostics and therapy so that early and effective detection of cavitation is of great interest. However, cavitation might even bring a higher risk especially when an echocontrast agent based on microbubbles is used. The major goal of the present work was to develop a cavitation detection method based on increased level of cavitation noise in the range of low frequencies ( about 1 Hz). This method was applied in vitro using a model of body fluid containing a model echocontrast agent, such as 5% solution of lyophilized egg albumin, which was sonicated by ultrasound disintegrator. Ultrasound signal evokes cavitation in microbubble suspension accompanied by a certain level of cavitation acoustic noise. The level of noise voltage increased in the frequency range of 0.1 to 2 Hz in the presence of cavitation. Hence, this method makes it possible to determine the value of cavitation threshold. In addition, we examined how the cavitation threshold is affected by temperature and viscosity. It was found that the cavitation threshold decreased with growing temperature while it increased with growing viscosity.