ŠIMARA, Pavel, Irena KOUTNÁ, Stanislav STEJSKAL, Martina PETERKOVÁ, Petr KRONTORÁD and Zdeněk RUČKA. Large-scale Microarray Analysis of Protein and mRNA Level Changes in HL-60 Cells. 2007.
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Basic information
Original name Large-scale Microarray Analysis of Protein and mRNA Level Changes in HL-60 Cells
Name in Czech Genomická a proteomická analýza buněk HL-60 pomocí microarray technologie.
Authors ŠIMARA, Pavel (203 Czech Republic, guarantor, belonging to the institution), Irena KOUTNÁ (203 Czech Republic, belonging to the institution), Stanislav STEJSKAL (203 Czech Republic, belonging to the institution), Martina PETERKOVÁ (203 Czech Republic, belonging to the institution), Petr KRONTORÁD (203 Czech Republic, belonging to the institution) and Zdeněk RUČKA (203 Czech Republic).
Edition 2007.
Other information
Original language English
Type of outcome Audiovisual works
Field of Study 10601 Cell biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14330/07:00022540
Organization unit Faculty of Informatics
Keywords in English HL-60; microarrays
Tags HL-60, microarrays
Tags International impact
Changed by Changed by: Mgr. Pavel Šimara, Ph.D., učo 67594. Changed: 2/3/2018 10:26.
Abstract
In this study we compare methods for large-scale microarray analysis of protein and RNA level changes in HL-60 cells, responding to differentiation stimuli. Using microarrays we have found, that level of several proteins was either up- or down-regulated after cell differentiation. In some cases there was significant correlation with appropriate genes.
Abstract (in Czech)
V této studii porovnáváme genomický a proteomický profil buněk HL-60.
Links
MSM0021622430, plan (intention)Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Research Intents
2B06052, research and development projectName: Vytipování markerů, screening a časná diagnostika nádorových onemocnění pomocí vysoce automatizovaného zpracování multidimenzionálních biomedicínských obrazů (Acronym: Biomarker)
Investor: Ministry of Education, Youth and Sports of the CR, Health and quality of life
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