SUCHOMELOVÁ, Jana and Eva TÁBORSKÁ. Changes in content of benzophenanthridine alkaloids in three species of the family Papaveraceae during the vegetation period. In Planta Medica. 2007th ed. Stuttgart: Planta Medica, 2007, p. 860.
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Basic information
Original name Changes in content of benzophenanthridine alkaloids in three species of the family Papaveraceae during the vegetation period
Name in Czech Změny v obsahu benzofenanthridinových alkaloidů u třech druzích čeledi Papaveraceae v průbehu vegetace
Authors SUCHOMELOVÁ, Jana (203 Czech Republic) and Eva TÁBORSKÁ (203 Czech Republic, guarantor).
Edition 2007. vyd. Stuttgart, Planta Medica, p. 860-860, 2007.
Publisher Planta Medica
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 40100 4.1 Agriculture, Forestry, and Fisheries
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/07:00020449
Organization unit Faculty of Medicine
UT WoS 000249395900326
Keywords in English Papaveraceae; benzophenathridine alkaloids
Tags benzophenathridine alkaloids, Papaveraceae
Tags International impact, Reviewed
Changed by Changed by: Mgr. Jana Gregorová, Ph.D., učo 152400. Changed: 27/6/2009 12:13.
Abstract
Some species of the family Papaveraceae, especially Dicranostigma lactucoides (HOOK.f.et THOMS), Macleaya microcarpa (Willd.), and Stylophorum lasiocarpum (Oliv.), are known by their high content of quaternary benzo[c]phenanthridine alkaloids (QBAs) in roots. The QBAs are divided into two groups. The main QBAs are sanguinarine (SA) and chelerythrine (CHE) and the minor are chelirubine (CHR), chelilutine (CHL), [sanguilutine (SL), sanguirubine (SR) ] and macarpine (MAC). The main QBAs show very wide range of biological activities, such as antimicrobial, antiinflamatory, antifungal activity, interact with many enzymes, inhibit microtubule assembly and interact with DNA. On the other hand, the knowledge about the effects of minor QBAs is very poor. The aim was to determine the best period for the collection of plants and the subsequent isolation of minor quaternary benzophenanthridine alkaloids.
Abstract (in Czech)
Některé druhy čeledi Papaveraceae především: Dicranostigma lactucoides (HOOK.f.et THOMS), Macleaya microcarpa (Willd.), a Stylophorum lasiocarpum (Oliv.), jsou známy svým vysokým obsahem quarterních benzo[c]fenanthridine (KBA) alkaloidů v kořenech. Mnoho publikací se zabývá biologickými účinky hlavních KBA.Na druhé straně, znalosti o účincích minoritních KBA jsou velmi chudé.Cílem této práce bylo vybrat nejlepší dobu pro sběr rostlin a následnou izolaci minoritních KBA.
Links
GA525/04/0017, research and development projectName: Rostlinné zdroje benzofenanthridinových alkaloidů a účinek těchto alkaloidů na normální a nádorové buňky
Investor: Czech Science Foundation, Plant sources of benzophenanthridine alkaloids and effects of these alkaloid on normal and cancer cells
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