SALZMAN, Richard, Kateřina KAŇKOVÁ, Lukáš PÁCAL, Josef TOMANDL, Kateřina ŠÍROVÁ and Rom KOSTŘICA. Increased activity of superoxid dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases. Neoplasma. Blarislava, Slovakia: Slovak Academy of Sciences, 2007, vol. 54, No 4, p. 321-325. ISSN 0028-2685.
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Basic information
Original name Increased activity of superoxid dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases
Name in Czech Increased activity of superoxid dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases
Authors SALZMAN, Richard (703 Slovakia, guarantor, belonging to the institution), Kateřina KAŇKOVÁ (203 Czech Republic, belonging to the institution), Lukáš PÁCAL (203 Czech Republic, belonging to the institution), Josef TOMANDL (203 Czech Republic, belonging to the institution), Kateřina ŠÍROVÁ (203 Czech Republic) and Rom KOSTŘICA (203 Czech Republic, belonging to the institution).
Edition Neoplasma, Blarislava, Slovakia, Slovak Academy of Sciences, 2007, 0028-2685.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.208
RIV identification code RIV/00216224:14110/07:00019091
Organization unit Faculty of Medicine
UT WoS 000251196300009
Keywords in English antioxidative enzymes; head and neck cancer; metastasis; oxidative stress; polymorphism; syuperoxide dismutase
Tags antioxidative enzymes, head and neck cancer, metastasis, oxidative stress, polymorphism, syuperoxide dismutase
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Josef Tomandl, Ph.D., učo 47. Changed: 6/6/2012 08:39.
Abstract
Our results suggest that increased p-SOD at the time of the initial treatment for HNSCC is connected with a greater extent and nodal metastatic spread of the initial disease and an earlier disease relapse. Progression of diseases might be further modified by the presence of Ala/Ala genotype of the SOD2. Activity of p-SOD could thus offer diagnostic as well as prognostic value.
Abstract (in Czech)
Our results suggest that increased p-SOD at the time of the initial treatment for HNSCC is connected with a greater extent and nodal metastatic spread of the initial disease and an earlier disease relapse. Progression of diseases might be further modified by the presence of Ala/Ala genotype of the SOD2. Activity of p-SOD could thus offer diagnostic as well as prognostic value.
Links
NR7996, research and development projectName: Polymorfismus antioxidativních enzymů ve vztahu ke krustózní tracheobronchitidě jako závažné komplikaci u tracheotomovaných pacientů
Investor: Ministry of Health of the CR
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