| WIMMEROVÁ, Michaela, Emilie LAMEIGNERE, Lenka MALINOVSKÁ, Charles SABIN, Jan ADAM, Martina POKORNÁ, Annabelle VARROT, Edward P. MITCHELL and Anne IMBERTY. High affinity lectins from human opportunistic pathogens: structure/function studies. In XIX International Symposium on Glycoconjugates. Cairns, Australie: IGO, 2007, p. 56-56. |
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@inproceedings{727651,
author = {Wimmerová, Michaela and Lameignere, Emilie and Malinovská, Lenka and Sabin, Charles and Adam, Jan and Pokorná, Martina and Varrot, Annabelle and Mitchell, Edward P. and Imberty, Anne},
address = {Cairns, Australie},
booktitle = {XIX International Symposium on Glycoconjugates},
keywords = {lectin; pathogen; x-ray structure; calorimetry},
language = {eng},
location = {Cairns, Australie},
pages = {56-56},
publisher = {IGO},
title = {High affinity lectins from human opportunistic pathogens: structure/function studies},
year = {2007}
}
TY - JOUR
ID - 727651
AU - Wimmerová, Michaela - Lameignere, Emilie - Malinovská, Lenka - Sabin, Charles - Adam, Jan - Pokorná, Martina - Varrot, Annabelle - Mitchell, Edward P. - Imberty, Anne
PY - 2007
TI - High affinity lectins from human opportunistic pathogens: structure/function studies
PB - IGO
CY - Cairns, Australie
KW - lectin
KW - pathogen
KW - x-ray structure
KW - calorimetry
N2 - The complementary techniques of binding experiments, isothermal titration microcalorimetry, surface plasmon resonance and high resolution X-ray crystallography were used to decipher the thermodynamical and structural basis for the unusually high affinity binding of these lectins to their host carbohydrates. In addition, site-directed mutagenesis in combination with structural and functional studies was used to understand the roles of particular amino acids in the fine definition of sugar specificity and preference.
ER -
WIMMEROVÁ, Michaela, Emilie LAMEIGNERE, Lenka MALINOVSKÁ, Charles SABIN, Jan ADAM, Martina POKORNÁ, Annabelle VARROT, Edward P. MITCHELL and Anne IMBERTY. High affinity lectins from human opportunistic pathogens: structure/function studies. In \textit{XIX International Symposium on Glycoconjugates}. Cairns, Australie: IGO, 2007, p.~56-56.
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