LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL, Michaela WIMMEROVÁ and Anne IMBERTY. 3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC) (Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)). In 14th European Carbohydrate Symposium, EUROCARB 14. Lubeck (Germany): Research Center Borstel and the Institute of Chemistry, 2007, p. X, 1 pp.
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Basic information
Original name 3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)
Name in Czech Strukturní a termodynamická charakterizace BclA, lektinu z Burkholderia cepacia komplexu (BCC)
Authors LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL, Michaela WIMMEROVÁ and Anne IMBERTY.
Edition Lubeck (Germany), 14th European Carbohydrate Symposium, EUROCARB 14, p. X, 1 pp. 2007.
Publisher Research Center Borstel and the Institute of Chemistry
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10600 1.6 Biological sciences
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Science
Keywords in English structure; lectin; pathogen; cepacia complex
Tags cepacia complex, lectin, pathogen, structure
Tags International impact
Changed by Changed by: prof. RNDr. Michaela Wimmerová, Ph.D., učo 854. Changed: 12/11/2007 18:14.
Abstract
Printed Glycan arrays performed by the Consortium for Functional Glycomics (CFG) demonstrated that BclA has a strict specificity for oligosaccharide with a terminal alpha-mannose residue. Thermodynamics of the interaction of BclA with methyl-mannoside and some other mannosylated oligosaccharides was studied by isothermal titration microcalorimetry (ITC). protein has been crystallized and the structure of the complex with the methyl-mannoside was solved at 1.7A resolution.
Abstract (in Czech)
BclA lektin byl strukturně a termodynamicky charakterizována jeho vysoká specifita vůči mannosylovaným sacharidům.
Links
LC06030, research and development projectName: Biomolekulární centrum
Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
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