3.	Structural and thermodynamical characterization of
BclA, a lectin from Burkholderia cepacia complex (BCC)

D 2007

3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)

LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL et. al.

Basic information

Original name

3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)

Name in Czech

Strukturní a termodynamická charakterizace BclA, lektinu z Burkholderia cepacia komplexu (BCC)

Authors

LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL, Michaela WIMMEROVÁ and Anne IMBERTY

Edition

Lubeck (Germany), 14th European Carbohydrate Symposium, EUROCARB 14, p. X, 1 pp. 2007

Publisher

Research Center Borstel and the Institute of Chemistry

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Science

Keywords in English

structure; lectin; pathogen; cepacia complex

Abstract

ORIG CZ

V originále

Printed Glycan arrays performed by the Consortium for Functional Glycomics (CFG) demonstrated that BclA has a strict specificity for oligosaccharide with a terminal alpha-mannose residue. Thermodynamics of the interaction of BclA with methyl-mannoside and some other mannosylated oligosaccharides was studied by isothermal titration microcalorimetry (ITC). protein has been crystallized and the structure of the complex with the methyl-mannoside was solved at 1.7A resolution.

In Czech

BclA lektin byl strukturně a termodynamicky charakterizována jeho vysoká specifita vůči mannosylovaným sacharidům.

Links

LC06030, research and development project

Name: Biomolekulární centrum

Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre

MSM0021622413, plan (intention)

Name: Proteiny v metabolismu a při interakci organismů s prostředím

Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment

Citovat

LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL, Michaela WIMMEROVÁ and Anne IMBERTY. 3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC) (Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)). In 14th European Carbohydrate Symposium, EUROCARB 14. Lubeck (Germany): Research Center Borstel and the Institute of Chemistry, 2007, p. X, 1 pp.

@inproceedings{727656,
   author = {Lameignere, Emilie and Malinovská, Lenka and Varrot, Annabelle and Sláviková, Margita and Mitchell, Edward P. and Wimmerová, Michaela and Imberty, Anne},
   address = {Lubeck (Germany)},
   booktitle = {14th European Carbohydrate Symposium, EUROCARB 14},
   keywords = {structure; lectin; pathogen; cepacia complex},
   language = {eng},
   location = {Lubeck (Germany)},
   pages = {X},
   publisher = {Research Center Borstel and the Institute of Chemistry},
   title = {3.   Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)},
   year = {2007}
}

TY  - JOUR
ID  - 727656
AU  - Lameignere, Emilie - Malinovská, Lenka - Varrot, Annabelle - Sláviková, Margita - Mitchell, Edward P. - Wimmerová, Michaela - Imberty, Anne
PY  - 2007
TI  - 3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)
PB  - Research Center Borstel and the Institute of Chemistry
CY  - Lubeck (Germany)
KW  - structure
KW  - lectin
KW  - pathogen
KW  - cepacia complex
N2  - Printed Glycan arrays performed by the Consortium for Functional Glycomics (CFG) demonstrated that BclA has a strict specificity for oligosaccharide with a terminal alpha-mannose residue. Thermodynamics of the interaction of BclA with methyl-mannoside and some other mannosylated oligosaccharides was studied by isothermal titration microcalorimetry (ITC). protein has been crystallized and the structure of the complex with the methyl-mannoside was solved at 1.7A resolution.
ER  -

LAMEIGNERE, Emilie, Lenka MALINOVSKÁ, Annabelle VARROT, Margita SLÁVIKOVÁ, Edward P. MITCHELL, Michaela WIMMEROVÁ and Anne IMBERTY. 3. Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC) (Structural and thermodynamical characterization of BclA, a lectin from Burkholderia cepacia complex (BCC)). In \textit{14th European Carbohydrate Symposium, EUROCARB 14}. Lubeck (Germany): Research Center Borstel and the Institute of Chemistry, 2007, p.~X, 1 pp.

Detailed Information on Publication Record