Among present known biological functions of lactoferrin belong homeostasis of iron maintenance. This is set in small intestine, where is the iron taken from food. Interesting is relation to cell growth regulation, cell differentiation and anti-inflammatory activity. It also follows possible relation to maligne tumors and metastasis process. Electrochemical methods represent alternative tool for detection of biologically active matters primarily for their simplicity, rapidity and reliability. The aim of this paper was the basic electrochemical study of lactoferrin by stationary and flow electrochemical techniques with application for structural changes distinguishing.