Determination of Metallothionein Content in Patients with Tumor
Diseases

D 2007

Determination of Metallothionein Content in Patients with Tumor Diseases

HORNA, Aleš, Libuše TRNKOVÁ, Ondřej BLAŠTÍK, Ondřej ZÍTKA, René KIZEK et. al.

Basic information

Original name

Determination of Metallothionein Content in Patients with Tumor Diseases

Name in Czech

Stanovení obsahu metalothioneinu u pacientů s nádorovým onemocněním

Authors

HORNA, Aleš, Libuše TRNKOVÁ, Ondřej BLAŠTÍK, Ondřej ZÍTKA, René KIZEK, Richard PRŮŠA and Vojtěch ADAM

Edition

McCormick Place, Chicago, USA, Pittcon 2007, p. 1410-1410, 1 pp. 2007

Publisher

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Inc.

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Science

Keywords in English

Metallothionein; tumor diseases; electrochemistry

Abstract

ORIG CZ

V originále

A few millions of patients with tumour diseases are diagnosed worldwide per year. Recently, it was discovered that content of metallothionein (MT)changes with different tumour diseases such as breast cancer, melanoma, pancreas cancer etc. The changes in MT expression could be used as a prognostic marker of a tumour disease. So, investigation of the changes of MT expression at patients using simple and rapid analytical techniques is needed. The aim of this work was to develop a new rapid and highly sensitive analytic method for MT. Determination of MT was performed by modified differential pulse voltammetry in connection with adsorptive transfer stripping voltammetry.

In Czech

Každý rok je diagnostikováno na rakovinu několik milionů lidí. Nedávno bylo zjištěno, že obsah metalothioneinu (MT)se mění s různými nádorovými onemocněními jako rakovina prsu, melanom, rakovina slinivky atd. Změny v expresi MT by mohly být použity jako prognostický marker nádorových onemocnění. Je tedy potřeba vyvinout rychlou a jednoduchou analytickou techniku pro zjištění změny exprese MT. Snahou této studie bylo vyvinout novou rychlou a vysoce senzitivní analytickou metodu pro MT. Stanovení MT bylo provedeno modifikovanou diferenční pulzní voltametrií ve spojení s adsorptivní přínosovou rozpouštěcí voltametrií.

Citovat

HORNA, Aleš, Libuše TRNKOVÁ, Ondřej BLAŠTÍK, Ondřej ZÍTKA, René KIZEK, Richard PRŮŠA and Vojtěch ADAM. Determination of Metallothionein Content in Patients with Tumor Diseases. In Pittcon 2007. McCormick Place, Chicago, USA: The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Inc., 2007, p. 1410-1410.

@inproceedings{746858,
   author = {Horna, Aleš and Trnková, Libuše and Blaštík, Ondřej and Zítka, Ondřej and Kizek, René and Průša, Richard and Adam, Vojtěch},
   address = {McCormick Place, Chicago, USA},
   booktitle = {Pittcon 2007},
   keywords = {Metallothionein; tumor diseases; electrochemistry},
   language = {eng},
   location = {McCormick Place, Chicago, USA},
   pages = {1410-1410},
   publisher = {The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Inc.},
   title = {Determination of Metallothionein Content in Patients with Tumor Diseases},
   year = {2007}
}

TY  - JOUR
ID  - 746858
AU  - Horna, Aleš - Trnková, Libuše - Blaštík, Ondřej - Zítka, Ondřej - Kizek, René - Průša, Richard - Adam, Vojtěch
PY  - 2007
TI  - Determination of Metallothionein Content in Patients with Tumor Diseases
PB  - The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Inc.
CY  - McCormick Place, Chicago, USA
KW  - Metallothionein
KW  - tumor diseases
KW  - electrochemistry
N2  - A few millions of patients with tumour diseases are diagnosed worldwide per year. Recently, it was discovered that content of metallothionein (MT)changes with different tumour diseases such as breast cancer, melanoma, pancreas cancer etc. The changes in MT expression could be used as a prognostic marker of a tumour disease. So, investigation of the changes of MT expression at patients using simple and rapid analytical techniques is needed. The aim of this work was to develop a new rapid and highly sensitive analytic method for MT. Determination of MT was performed by modified differential pulse voltammetry in connection with adsorptive transfer stripping voltammetry.
ER  -

HORNA, Aleš, Libuše TRNKOVÁ, Ondřej BLAŠTÍK, Ondřej ZÍTKA, René KIZEK, Richard PRŮŠA and Vojtěch ADAM. Determination of Metallothionein Content in Patients with Tumor Diseases. In \textit{Pittcon 2007}. McCormick Place, Chicago, USA: The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Inc., 2007, p.~1410-1410.

Detailed Information on Publication Record