KOUTNÁ, Irena, Lenka TESAŘOVÁ, Martin KLABUSAY, Petr KROTORÁD, Michal STREHOVSKÝ, Martina PETERKOVÁ and Viera HRABČÁKOVÁ. Expression Profiling of CD34+ of Peripheral Blood of Patients with Lymphoma During ex vivo Granulocytic Differentiation. 2007.
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Basic information
Original name Expression Profiling of CD34+ of Peripheral Blood of Patients with Lymphoma During ex vivo Granulocytic Differentiation
Name in Czech Expresní profilování CD34+ buněk z periferní krve pacientů s lymfomem během granulocytické diferenciace ex vivo
Authors KOUTNÁ, Irena (203 Czech Republic, guarantor), Lenka TESAŘOVÁ (203 Czech Republic), Martin KLABUSAY (203 Czech Republic), Petr KROTORÁD (203 Czech Republic), Michal STREHOVSKÝ (703 Slovakia), Martina PETERKOVÁ (203 Czech Republic) and Viera HRABČÁKOVÁ (703 Slovakia).
Edition 2007.
Other information
Original language English
Type of outcome Audiovisual works
Field of Study Genetics and molecular biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14330/07:00023259
Organization unit Faculty of Informatics
Keywords in English CD34+; cDNA microarrays; lymphoma
Tags cbia-web, CD34+, cDNA microarrays, Lymphoma
Tags International impact
Changed by Changed by: doc. RNDr. Irena Koutná, Ph.D., učo 18705. Changed: 9/1/2008 16:46.
Abstract
On the basis of global expression data analysis we have concluded that population of CD34+ cells from patients with lymphoma shows different expression status during ex-vivo differentiation. And thus we assume that CD34+ population is not suitable for autologous transplantation. We have used cDNA microarrays technology to obtained precise expression profiles.
Abstract (in Czech)
Na základě globální expresní analýzy pomocí cDNA microarrays jsme zjistili, že populace CD34+ buněk získaná od pacientů s lymfomem vykazuje během ex vivo diferenciace rozdílné expresní profily. Z výsledků vyplývá, že populace CD34+ buněk není vhodná pro autologní transplantaci.
Links
MSM0021622430, plan (intention)Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
2B06052, research and development projectName: Vytipování markerů, screening a časná diagnostika nádorových onemocnění pomocí vysoce automatizovaného zpracování multidimenzionálních biomedicínských obrazů (Acronym: Biomarker)
Investor: Ministry of Education, Youth and Sports of the CR, Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images
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