MAČÁK, Jirka, Jana ŠMARDOVÁ, Iva KROUPOVÁ, Barbora RAVČUKOVÁ, Martin KLABUSAY and Leoš KŘEN. Heterogeneity of mantle cell lymphoma. Virchows Archiv. Německo: Springer Verlag, vol. 451, No 2, p. 432. ISSN 0945-6317. 2007.
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Basic information
Original name Heterogeneity of mantle cell lymphoma
Name in Czech Heterogenita lymfomu z buněk plášťové zóny
Name (in English) Heterogeneity of mantle cell lymphoma
Authors MAČÁK, Jirka, Jana ŠMARDOVÁ, Iva KROUPOVÁ, Barbora RAVČUKOVÁ, Martin KLABUSAY and Leoš KŘEN.
Edition Virchows Archiv, Německo, Springer Verlag, 2007, 0945-6317.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.029
Organization unit Faculty of Medicine
UT WoS 000249454600976
Keywords in English mantle cell lymphoma; immunohistochemistry; molecular biology
Tags Immunohistochemistry, mantle cell lymphoma, molecular biology
Changed by Changed by: prof. MUDr. Jirka Mačák, CSc., učo 133065. Changed: 22/1/2008 07:01.
Abstract
Results show that MCL was uniform in morphology and in type of infiltration, which was in all cases diffuse. Very useful marker for diagnosis seems to be hyaline deposits scattered in the lymphoma tissue. Number of mitoses enable us include 6 cases to the blastoid variant of MCL. In immunohistochemistry, CD5 and cyclinD-1 markers were negative in 30 % of cases. Mutation of p53 gene is rare in MCL. In our series were found two cases with mutation of gene p53.
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