D 2007

Organization of nano-scale synthetic oligonucleotides on immersed electrode surface: an optical study.

SILVENNOINEN, Raimo, Stanislav HASOŇ and Vladimír VETTERL

Basic information

Original name

Organization of nano-scale synthetic oligonucleotides on immersed electrode surface: an optical study.

Name in Czech

Organizace xxxx

Authors

SILVENNOINEN, Raimo, Stanislav HASOŇ and Vladimír VETTERL

Edition

Tampere (Finland), Technical digest, p. 101-102, 2 pp. 2007

Publisher

University Joensuu

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10610 Biophysics

Country of publisher

Finland

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

Keywords in English

diffractive optical element; permittivity; optical roughness; electrode surface;

Tags

International impact, Reviewed
Změněno: 30/6/2008 14:09, prof. RNDr. Vladimír Vetterl, DrSc.

Abstract

V originále

Organization of nano-scale molecules as oligodeoxynucleotides (ODN) or blood plasma proteins attached on electrode surface, which is located in liquids, is an interesting phenomenon. Thus the need to develop novel methods to detect this organization is arisen from the observation that conventional surface characterization methods and tools are observed to be un-effective when a need is to make observation from a sample in a liquid. We report results from our recent investigations, which are extended to sense organization of nano-scale molecules adhered on electrode surface. The permittivity change and the fluctuations in optical roughness of an electrode surface is investigated through an optical window of an cuvette by using the DOE sensor, when the molecules injected in the immersion liquid are adsorbed on the electrode surface.

In Czech

Organisace molekul o nanorozměrech jako jsou oligodeoxynukleotidy nabo bílkoviny krevní plazmy přichycených na elektrodovém povrchu umístěném v kapalině je zajímavý jev. K jeho studiu vznikla potřeba vyvinout nové metody umožňující stanovit tuto organisaci v kapalném prostředí, kde obvyklé metody charakterisující povrchové vlastnosti jsou nepoužitelné. Pomocí difrakčního optického sensoru (DOE) jsme studovali změny permitivity a fluktuace optické drsnosti po adsorpci molekul oligodeoxynukleotidů a fibrinogenu na povrch elektrody.

Links

IAA4004404, research and development project
Name: Interakce biopolymerů s ligandy a detekce jejich konformačních změn na fázových rozhraních pomocí elektrochemických a optických metod
Investor: Academy of Sciences of the Czech Republic, Interaction of biopolymers with ligands and detection of their conformation changes at interfaces by electrochemical and optical methods.
1M0528, research and development project
Name: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre