STOLYAROVA, Sara, Cherian SUMAN, Roberto RAITERI, Jiří ŽERAVÍK, Petr SKLÁDAL and Yael NEMIROVSKY. Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing. Sensors and Actuators B Chemical. Amsterdam (Holandsko): Elsevier, 2008, vol. 131, No 1, p. 509-515. ISSN 0925-4005.
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Basic information
Original name Composite Porous Silicon-Crystalline Silicon Cantilevers for Enhanced Biosensing
Name in Czech Kompozitní kantilevry na bázi porézního křemíku a krystalického křemíku pro vylepšení biosensorů
Authors STOLYAROVA, Sara (376 Israel), Cherian SUMAN (356 India), Roberto RAITERI (380 Italy), Jiří ŽERAVÍK (203 Czech Republic), Petr SKLÁDAL (203 Czech Republic, guarantor) and Yael NEMIROVSKY (376 Israel).
Edition Sensors and Actuators B Chemical, Amsterdam (Holandsko), Elsevier, 2008, 0925-4005.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.122
RIV identification code RIV/00216224:14310/08:00025703
Organization unit Faculty of Science
UT WoS 000256116100022
Keywords in English Porous silicon; Microcantilever; Antibody; Silanization; Fluorescence label
Tags antibody, Fluorescence label, microcantilever, POROUS SILICON, Silanization
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Petr Skládal, CSc., učo 2202. Changed: 29/6/2009 16:24.
Abstract
Cantilever transducers, which are recognized as a promising platform for the next generation of chemical and biological sensors, are currently under extensive research. Here we report composite porous silicon-crystalline silicon microcantilevers made of SOI wafers, where the porous silicon surface provides an excellent interface for immobilization of the biosensing layer. We start with crystalline silicon cantilevers fabricated from SOI wafers and we establish a surface layer of porous silicon on the cantilevers by vapor phase stain etching. The processed porous silicon does not introduce signi?cant static bending of the cantilevers indicating that it does not introduce signi?cant residual stress. It does provide an excellent biocompatible material for immobilization of a wide variety of chemical and biological materials, resulting in enhanced sensitivity as demonstrated on the covalently immobilized antibody binding its complementary antigen.
Abstract (in Czech)
Metodika modifikace povrchu porézního křemíku na bázi silanizace, vhodná pro imobilizaci protilátek na povrch kantilevrů - nanomechanických převodníků pro biosensory.
Links
LC06030, research and development projectName: Biomolekulární centrum
Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
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