| ADEWUMI, O., B. AFLATOONIAN, L. AHRLUND-RICHTER, M. AMIT, P.W. ANDREWS, G. BEIGHTON, P.A. BELLO, N. BENVENISTY, L.S. BERRY, S. BEVAN, B. BLUM, J. BROOKING, K.G. CHEN, A.B. CHOO, G.A. CHURCHILL, M. CORBEL, I. DAMJANOV, J.S. DRAPER, Petr DVOŘÁK, K. EMANUELSSON, R.A. FLECK, A. FORD, K. GERTOW, M. GERTSENSTEIN, P.J. GOKHALE, R.S. HAMILTON, Aleš HAMPL, L.E. HEALY, O. HOVATTA, J. HYLLNER, M.P. IMREH, J. ITSKOVITZ-ELDOR, J. JACKSON, J.L. JOHNSON, M. JONES, K. KEE, B.L. KING, B.B. KNOWLES, M. LAKO, F. LEBRIN, B.S. MALLON, D. MANNING, Y. MAYSHAR, R.D. MCKAY, A.E. MICHALSKA, M. MIKKOLA, M. MILEIKOVSKY, S.L. MINGER, H.D. MOORE, C.L. MUMMERY, A. NAGY, N. NAKATSUJI, C.M. O´BRIEN, S.K. OH, C. OLSSON, T. OTONKOSKI, K.Y. PARK, R. PASSIER, H. PATEL, M. PATEL, R. PEDERSEN, M.F. PERA, M.S. PIEKARCZYK, R.A. PERA, B.E. REUBINOFF, A.J. ROBINS, J. ROSSANT, P. RUGG-HUNN, T.C. SCHULZ, H. SEMB, E.S. SHERRER, H. SIEMEN, G.N. STACEY, M. STOJKOVIC, H. SUEMORI, J. SZATKIEWICZ, T. TURETSKY, T. TUURI, S. VAN DEN BRINK, K. VINTERSTEN, S. VUORISTO, D. WARD, T.A. WEAVER, L.A. YOUNG and W. ZHANG. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature biotechnology. 2007, vol. 25, No 7, p. 803-816. ISSN 1087-0156. |
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@article{750467,
author = {Adewumi, O. and Aflatoonian, B. and AhrlundandRichter, L. and Amit, M. and Andrews, P.W. and Beighton, G. and Bello, P.A. and Benvenisty, N. and Berry, L.S. and Bevan, S. and Blum, B. and Brooking, J. and Chen, K.G. and Choo, A.B. and Churchill, G.A. and Corbel, M. and Damjanov, I. and Draper, J.S. and Dvořák, Petr and Emanuelsson, K. and Fleck, R.A. and Ford, A. and Gertow, K. and Gertsenstein, M. and Gokhale, P.J. and Hamilton, R.S. and Hampl, Aleš and Healy, L.E. and Hovatta, O. and Hyllner, J. and Imreh, M.P. and ItskovitzandEldor, J. and Jackson, J. and Johnson, J.L. and Jones, M. and Kee, K. and King, B.L. and Knowles, B.B. and Lako, M. and Lebrin, F. and Mallon, B.S. and Manning, D. and Mayshar, Y. and McKay, R.D. and Michalska, A.E. and Mikkola, M. and Mileikovsky, M. and Minger, S.L. and Moore, H.D. and Mummery, C.L. and Nagy, A. and Nakatsuji, N. and O´Brien, C.M. and Oh, S.K. and Olsson, C. and Otonkoski, T. and Park, K.Y. and Passier, R. and Patel, H. and Patel, M. and Pedersen, R. and Pera, M.F. and Piekarczyk, M.S. and Pera, R.A. and Reubinoff, B.E. and Robins, A.J. and Rossant, J. and RuggandHunn, P. and Schulz, T.C. and Semb, H. and Sherrer, E.S. and Siemen, H. and Stacey, G.N. and Stojkovic, M. and Suemori, H. and Szatkiewicz, J. and Turetsky, T. and Tuuri, T. and Van den Brink, S. and Vintersten, K. and Vuoristo, S. and Ward, D. and Weaver, T.A. and Young, L.A. and Zhang, W.},
article_number = {7},
keywords = {human; embryonic; stem cell},
language = {eng},
issn = {1087-0156},
journal = {Nature biotechnology},
title = {Characterization of human embryonic stem cell lines by the International Stem Cell Initiative},
volume = {25},
year = {2007}
}
TY - JOUR
ID - 750467
AU - Adewumi, O. - Aflatoonian, B. - Ahrlund-Richter, L. - Amit, M. - Andrews, P.W. - Beighton, G. - Bello, P.A. - Benvenisty, N. - Berry, L.S. - Bevan, S. - Blum, B. - Brooking, J. - Chen, K.G. - Choo, A.B. - Churchill, G.A. - Corbel, M. - Damjanov, I. - Draper, J.S. - Dvořák, Petr - Emanuelsson, K. - Fleck, R.A. - Ford, A. - Gertow, K. - Gertsenstein, M. - Gokhale, P.J. - Hamilton, R.S. - Hampl, Aleš - Healy, L.E. - Hovatta, O. - Hyllner, J. - Imreh, M.P. - Itskovitz-Eldor, J. - Jackson, J. - Johnson, J.L. - Jones, M. - Kee, K. - King, B.L. - Knowles, B.B. - Lako, M. - Lebrin, F. - Mallon, B.S. - Manning, D. - Mayshar, Y. - McKay, R.D. - Michalska, A.E. - Mikkola, M. - Mileikovsky, M. - Minger, S.L. - Moore, H.D. - Mummery, C.L. - Nagy, A. - Nakatsuji, N. - O´Brien, C.M. - Oh, S.K. - Olsson, C. - Otonkoski, T. - Park, K.Y. - Passier, R. - Patel, H. - Patel, M. - Pedersen, R. - Pera, M.F. - Piekarczyk, M.S. - Pera, R.A. - Reubinoff, B.E. - Robins, A.J. - Rossant, J. - Rugg-Hunn, P. - Schulz, T.C. - Semb, H. - Sherrer, E.S. - Siemen, H. - Stacey, G.N. - Stojkovic, M. - Suemori, H. - Szatkiewicz, J. - Turetsky, T. - Tuuri, T. - Van den Brink, S. - Vintersten, K. - Vuoristo, S. - Ward, D. - Weaver, T.A. - Young, L.A. - Zhang, W.
PY - 2007
TI - Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
JF - Nature biotechnology
VL - 25
IS - 7
SP - 803-816
EP - 803-816
SN - 10870156
KW - human
KW - embryonic
KW - stem cell
N2 - This study represents the result of the first international comparison of a large number of lines of human embryonic (ES) stem cells from laboratories worldwide that has been accomplished with the aim to reveal and characterize their similarities and/or differences. In this study, we have analyzed 59 independently derived human ES cell lines, from 17 laboratories in 11 countries. Our data show that despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibit similar expression patterns for several markers of human ES cells. Nevertheless, the lines were not identical: differences in expression of several lineage-specific markers were evident, and several imprinted genes showed generally similar allele-specific expression patterns. This study sets grounds for further international collaboration toward the future use of human ES cells in regenerative medicine, drug discovery and toxicology.
ER -
ADEWUMI, O., B. AFLATOONIAN, L. AHRLUND-RICHTER, M. AMIT, P.W. ANDREWS, G. BEIGHTON, P.A. BELLO, N. BENVENISTY, L.S. BERRY, S. BEVAN, B. BLUM, J. BROOKING, K.G. CHEN, A.B. CHOO, G.A. CHURCHILL, M. CORBEL, I. DAMJANOV, J.S. DRAPER, Petr DVOŘÁK, K. EMANUELSSON, R.A. FLECK, A. FORD, K. GERTOW, M. GERTSENSTEIN, P.J. GOKHALE, R.S. HAMILTON, Aleš HAMPL, L.E. HEALY, O. HOVATTA, J. HYLLNER, M.P. IMREH, J. ITSKOVITZ-ELDOR, J. JACKSON, J.L. JOHNSON, M. JONES, K. KEE, B.L. KING, B.B. KNOWLES, M. LAKO, F. LEBRIN, B.S. MALLON, D. MANNING, Y. MAYSHAR, R.D. MCKAY, A.E. MICHALSKA, M. MIKKOLA, M. MILEIKOVSKY, S.L. MINGER, H.D. MOORE, C.L. MUMMERY, A. NAGY, N. NAKATSUJI, C.M. O´BRIEN, S.K. OH, C. OLSSON, T. OTONKOSKI, K.Y. PARK, R. PASSIER, H. PATEL, M. PATEL, R. PEDERSEN, M.F. PERA, M.S. PIEKARCZYK, R.A. PERA, B.E. REUBINOFF, A.J. ROBINS, J. ROSSANT, P. RUGG-HUNN, T.C. SCHULZ, H. SEMB, E.S. SHERRER, H. SIEMEN, G.N. STACEY, M. STOJKOVIC, H. SUEMORI, J. SZATKIEWICZ, T. TURETSKY, T. TUURI, S. VAN DEN BRINK, K. VINTERSTEN, S. VUORISTO, D. WARD, T.A. WEAVER, L.A. YOUNG and W. ZHANG. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. \textit{Nature biotechnology}. 2007, vol.~25, No~7, p.~803-816. ISSN~1087-0156.
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