FLEGROVÁ, Zuzana, Michal ŠKAREK, Tomáš BARTOŠ, Pavel ČUPR and Ivan HOLOUBEK. Usefulness of three SOS-response tests for genotoxicity detection. Fresenius Environmental Bulletin. 2007, vol. 16, No 11, p. 1369-1376, 7 pp. ISSN 1018-4619.
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Basic information
Original name Usefulness of three SOS-response tests for genotoxicity detection.
Name in Czech viz.angl.
Authors FLEGROVÁ, Zuzana (203 Czech Republic, guarantor), Michal ŠKAREK (203 Czech Republic), Tomáš BARTOŠ (203 Czech Republic), Pavel ČUPR (203 Czech Republic) and Ivan HOLOUBEK (203 Czech Republic).
Edition Fresenius Environmental Bulletin, 2007, 1018-4619.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.429
RIV identification code RIV/00216224:14310/07:00023728
Organization unit Faculty of Science
UT WoS 000252003400010
Keywords in English genotoxicity RecA SOS response DPD2794 SOS chromotest umuC test
Changed by Changed by: prof. RNDr. Luděk Bláha, Ph.D., učo 15473. Changed: 25/6/2009 10:44.
Abstract
The RecA test, a luminescence SOS reporter test, and two well-known SOS reporter assays, umuC test and SOS chromotest, were compared. The main point of this study was to indicate the sensitivity of these tests. This was on the basis of comparison of effects on standard mutagens and environmental samples. The results with the selected chemicals showed that the RecA test was less sensitive in a qualitative way, in com-parison to the umuC test. However, its responses were quite comparable with the SOS chromotest. Results suggest that for our choice of environmental samples and chemical stan-dards the umuC test is optimal for genotoxicity detection, in comparison to RecA test and SOS chromotest.
Abstract (in Czech)
viz. angl.
Links
MSM0021622412, plan (intention)Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
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