The outcome of the research project was to verify the methodology of identification of industrial cluster potentials in southern Moravia region and to use this methodology for identification of concrete companies' potentials for clustering. The result of the project consists of the identification of companies with high potentials for clustering in the region of southern Moravia as well as the methodology for identification of such potentials in a region.. The methodology is based on analysis of the nature of co-operation of selected companies with other businesses, and it is verified by empirical research on the ample of 152 companies in the region of southern Moravia and 22 companies co-operating with the most advanced of them.