Antibacterial C-Geranylflavonoids from Paulownia tomentosa
Fruits

J 2008

Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits

ŠMEJKAL, Karel, Stanislav CHUDÍK, Pavel KLOUČEK, Radek MAREK, Josef CVAČKA et. al.

Basic information

Original name

Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits

Name in Czech

Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits

Authors

ŠMEJKAL, Karel (203 Czech Republic), Stanislav CHUDÍK (203 Czech Republic), Pavel KLOUČEK (203 Czech Republic), Radek MAREK (203 Czech Republic, guarantor, belonging to the institution), Josef CVAČKA (203 Czech Republic), Marie URBANOVÁ (203 Czech Republic), Ondřej JULÍNEK (203 Czech Republic), Ladislav KOKOŠKA (203 Czech Republic), Tereza ŠLAPETOVÁ (203 Czech Republic), Pavla HOLUBOVÁ (203 Czech Republic), Aleš ZIMA (203 Czech Republic) and Margita DVORSKÁ (203 Czech Republic)

Edition

Journal of Natural Products, Washington, American Chemical Society, 2008, 0163-3864

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

DOI: 10.1021/np070446u

Impact factor

Impact factor: 2.843

RIV identification code

RIV/00216224:14310/08:00025875

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1021/np070446u

UT WoS

000255339100037

Keywords in English

geranylflavonoid; Paulownia tomentosa; antibacterial; NMR

Abstract

ORIG CZ

V originále

Eight C-6-geranylflavonoids (1-8) were isolated from an ethanol extract of Paulownia tomentosa fruits. Tomentodiplacone (1), 3-O-methyl-5-hydroxydiplacone (2), 3-O-methyl-5-O-methyldiplacone (3), and tomentodiplacone B (4) were obtained as new compounds, and 3-O-methyldiplacol (5) was isolated for the first time from a natural source. The structures of these new compounds were determined by using mass spectrometry (including HRMS) and 1D and 2D NMR spectroscopy, and the absolute configurations of the compounds were determined by circular dichroism. The antibacterial activities of 1-8 against seven bacteria and yeast were evaluated.

In Czech

Izolace a strukturní charakterizace C-geranylflavonoidů s antibakteriální aktivitou.

Links

LC06030, research and development project

Name: Biomolekulární centrum

Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre

MSM0021622413, plan (intention)

Name: Proteiny v metabolismu a při interakci organismů s prostředím

Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment

Files attached

JNP08_71_706.pdf

Request the author's version of the file

Citovat

ŠMEJKAL, Karel, Stanislav CHUDÍK, Pavel KLOUČEK, Radek MAREK, Josef CVAČKA, Marie URBANOVÁ, Ondřej JULÍNEK, Ladislav KOKOŠKA, Tereza ŠLAPETOVÁ, Pavla HOLUBOVÁ, Aleš ZIMA and Margita DVORSKÁ. Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits. Journal of Natural Products. Washington: American Chemical Society, 2008, vol. 71, No 4, p. 706-709. ISSN 0163-3864. Available from: https://dx.doi.org/10.1021/np070446u.

@article{763747,
   author = {Šmejkal, Karel and Chudík, Stanislav and Klouček, Pavel and Marek, Radek and Cvačka, Josef and Urbanová, Marie and Julínek, Ondřej and Kokoška, Ladislav and Šlapetová, Tereza and Holubová, Pavla and Zima, Aleš and Dvorská, Margita},
   article_location = {Washington},
   article_number = {4},
   doi = {http://dx.doi.org/10.1021/np070446u},
   keywords = {geranylflavonoid; Paulownia tomentosa; antibacterial; NMR},
   language = {eng},
   issn = {0163-3864},
   journal = {Journal of Natural Products},
   title = {Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits},
   url = {http://dx.doi.org/10.1021/np070446u},
   volume = {71},
   year = {2008}
}

TY  - JOUR
ID  - 763747
AU  - Šmejkal, Karel - Chudík, Stanislav - Klouček, Pavel - Marek, Radek - Cvačka, Josef - Urbanová, Marie - Julínek, Ondřej - Kokoška, Ladislav - Šlapetová, Tereza - Holubová, Pavla - Zima, Aleš - Dvorská, Margita
PY  - 2008
TI  - Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits
JF  - Journal of Natural Products
VL  - 71
IS  - 4
SP  - 706
EP  - 706
PB  - American Chemical Society
SN  - 01633864
KW  - geranylflavonoid
KW  - Paulownia tomentosa
KW  - antibacterial
KW  - NMR
UR  - http://dx.doi.org/10.1021/np070446u
L2  - http://dx.doi.org/10.1021/np070446u
N2  - Eight C-6-geranylflavonoids (1-8) were isolated from an ethanol extract of Paulownia tomentosa fruits. Tomentodiplacone (1), 3-O-methyl-5-hydroxydiplacone (2), 3-O-methyl-5-O-methyldiplacone (3), and tomentodiplacone B (4) were obtained as new compounds, and 3-O-methyldiplacol (5) was isolated for the first time from a natural source. The structures of these new compounds were determined by using mass spectrometry (including HRMS) and 1D and 2D NMR spectroscopy, and the absolute configurations of the compounds were determined by circular dichroism. The antibacterial activities of 1-8 against seven bacteria and yeast were evaluated.
ER  -

ŠMEJKAL, Karel, Stanislav CHUDÍK, Pavel KLOUČEK, Radek MAREK, Josef CVAČKA, Marie URBANOVÁ, Ondřej JULÍNEK, Ladislav KOKOŠKA, Tereza ŠLAPETOVÁ, Pavla HOLUBOVÁ, Aleš ZIMA and Margita DVORSKÁ. Antibacterial C-Geranylflavonoids from Paulownia tomentosa Fruits. \textit{Journal of Natural Products}. Washington: American Chemical Society, 2008, vol.~71, No~4, p.~706-709. ISSN~0163-3864. Available from: https://dx.doi.org/10.1021/np070446u.

Detailed Information on Publication Record