KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA and Andrei ALEXANDROV. Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion. Online. Stroke : a journal of cerebral circulation. Dallas: American Heart Association, 2005, vol. 36, No 4, p. 869-871. ISSN 0039-2499. [citováno 2024-04-24]
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Basic information
Original name Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion
Name in Czech Četnost časné rekanalizace a klinický stav u pacientů se tandemovou okluzí arteria karotis interna/arteria cerebri media a izolovanou okluzí arteria cerebri media
Authors KIM, Jo Sik (410 Republic of Korea), Garami ZSOLT (348 Hungary), Robert MIKULÍK (203 Czech Republic, guarantor), Carlos MOLINA (724 Spain) and Andrei ALEXANDROV (840 United States of America)
Edition Stroke : a journal of cerebral circulation, Dallas, American Heart Association, 2005, 0039-2499.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 5.855
Organization unit Faculty of Medicine
UT WoS 000227523800148
Keywords in English stroke acute; outcome; ultrasonography; Doppler transcranial; thrombolysis
Tags Doppler transcranial, outcome, stroke acute, thrombolysis, Ultrasonography
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Robert Mikulík, Ph.D., učo 38765. Changed: 18/6/2009 13:48.
Abstract
Background: Patients with isolated middle cerebral artery (MCA) and tandem MCA/internal carotid artery (ICA)obstruction have similar presenting symptoms and stroke severity. We aimed to investigate early recanalization of MCA and clinical outcomes in patients with tandem ICA/MCA obstructions and isolated MCA occlusion. Methods: Patients with MCA occlusion on pretreatment transcranial Doppler were treated with intravenous tissue plasminogen activator. ICA lesions were detected with carotid duplex. Early neurological improvement (ENI) was defined by reduction of National Institutes of Health Stroke Scale (NIHSS) 10 or more points or total NIHSS 3 or less points. Good outcome at 3 months was a modified Rankin score of 2 or more. Results: Among 104 patients, 31% had tandem lesions and 69% had isolated MCA occlusions. Complete recanalization rate was 39% in isolated MCA occlusion group and 9% in tandem group (P=0.002). ENI at 24 hours occurred in 46% of the isolated MCA occlusion group and in 25% of the tandem group (P=0.045). Good outcome was achieved by 30% and 39% respective patients (NS). Conclusion: The tandem lesion group showed lower early recanalization rate and ENI rate than the isolated MCA occlusion group. Despite this, good outcomes were similar in both groups.
Abstract (in Czech)
Četnost časné rekanalizace a klinický stav u pacientů se tandemovou okluzí arteria karotis interna/arteria cerebri media byly horsi nez s izolovanou okluzí arteria cerebri media
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