HRDLIČKOVÁ, Barbara and Lydie IZAKOVIČOVÁ HOLLÁ. Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with allergic rhinitis in the Czech population. In Book of abstracts 15th ISCOMS. 2008. ISBN 978-90-367-3395-3.
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Basic information
Original name Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with allergic rhinitis in the Czech population
Name in Czech Asociace SNPs v genu pro eozinofilní peroxidázu u alergické rinitidy v české populaci
Authors HRDLIČKOVÁ, Barbara and Lydie IZAKOVIČOVÁ HOLLÁ.
Edition Book of abstracts 15th ISCOMS, 2008.
Other information
Original language English
Type of outcome Conference abstract
Field of Study Genetics and molecular biology
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
ISBN 978-90-367-3395-3
UT WoS 000266099200009
Keywords in English atopy; eosinophil peroxidase gene; polymorphism; rhinitis; SNP
Tags atopy, eosinophil peroxidase gene, polymorphism, rhinitis, SNP
Tags International impact, Reviewed
Changed by Changed by: Mgr. Barbara Hrdličková, učo 68363. Changed: 16/3/2010 08:54.
Abstract
The aim of this study was to analyze the eosinophil peroxidase gene (EPO) coding a cationic protein released from the specific granules of activated eosinophils. We attempted to locate the polymorphisms in the EPO gene typical for the Czech population and to analyse their association to allergic rhinitis and its intermediary phenotypes.
Abstract (in Czech)
Cílem této studie bylo analyzovat gen pro eozinofilní peroxidázu (EPO) kódující kationický protein uvolňovaný ze specifických granul aktivovaných eozinofilů. Rozhodli jsme se najít polymorfizmy v genu pro EPO typické pro českou populaci a analyzovat jejich asociaci s alergickou rinitidou a jejími intermediárními fenotypy.
Links
GA310/06/0827, research and development projectName: Genetické determinanty pro-/antioxidační rovnováhy v patogeneze respiračních nemocí
Investor: Czech Science Foundation
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