Off-Line Coupling of Capillary Electrophoresis to Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Elemental Speciation

PREISLER, Jan, Ondřej PEŠ, Pavla FOLTYNOVÁ, Radek VYHNÁNEK, Tomáš VACULOVIČ and Viktor KANICKÝ. Off-Line Coupling of Capillary Electrophoresis to Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Elemental Speciation. Denver, USA: ASMS, 2008. Proceedings of 56th ASMS Conference.

Basic information

• Original name: Off-Line Coupling of Capillary Electrophoresis to Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Elemental Speciation
• Name in Czech: Off-Line Coupling of Capillary Electrophoresis to Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Elemental Speciation
• Authors: PREISLER, Jan (203 Czech Republic, guarantor, belonging to the institution), Ondřej PEŠ (203 Czech Republic, belonging to the institution), Pavla FOLTYNOVÁ (203 Czech Republic, belonging to the institution), Radek VYHNÁNEK (203 Czech Republic, belonging to the institution), Tomáš VACULOVIČ (203 Czech Republic, belonging to the institution) and Viktor KANICKÝ (203 Czech Republic, belonging to the institution).
• Edition: Denver, USA, Proceedings of 56th ASMS Conference, 2008.
• Publisher: ASMS

Other information

• Original language: English
• Type of outcome: Audiovisual works
• Field of Study: 10406 Analytical chemistry
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL URL
• RIV identification code: RIV/00216224:14310/08:00026062
• Organization unit: Faculty of Science
• Keywords in English: Electrophoresis Capillary; Elemental Analysis; Laser Ablation; Mass Spectrometry; Inductively Coupled Plasma; Speciation
• Tags: Electrophoresis Capillary, elemental analysis, inductively coupled plasma, laser ablation, mass spectrometry, Speciation
• Tags: International impact

Abstract

On-line coupling of column separation techniques with inductively coupled plasma optical emission/mass spectrometry (ICP OES/MS) is routinely used for sensitive, element-selective analysis. Direct linking to ICP usually relies on a nebulizer, which often suffers from reduced separation resolution due to induced liquid flow. Here we report first off-line coupling of capillary electrophoresis (CE) with ICP MS, which is based on eluent deposition on a suitable target followed by laser ablation (LA) and transfer into ICP. The technique is compatible with microcolumn separations, such as capillary electrophoresis or nano liquid chromatography, in terms of both sensitivity and resolution. Furthermore, the fractions collected on the target can be archived and analyzed using other techniques, e.g. MALDI MS or laser-induced fluorescence.

Abstract (in Czech)

On-line coupling of column separation techniques with inductively coupled plasma optical emission/mass spectrometry (ICP OES/MS) is routinely used for sensitive, element-selective analysis. Direct linking to ICP usually relies on a nebulizer, which often suffers from reduced separation resolution due to induced liquid flow. Here we report first off-line coupling of capillary electrophoresis (CE) with ICP MS, which is based on eluent deposition on a suitable target followed by laser ablation (LA) and transfer into ICP. The technique is compatible with microcolumn separations, such as capillary electrophoresis or nano liquid chromatography, in terms of both sensitivity and resolution. Furthermore, the fractions collected on the target can be archived and analyzed using other techniques, e.g. MALDI MS or laser-induced fluorescence.

Links

• LC06035, research and development project: Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.

Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine

• MSM0021622411, plan (intention): Name: Studium a aplikace plazmochemických reakcí v neizotermickém nízkoteplotním plazmatu a jeho interakcí s povrchem pevných látek

Investor: Ministry of Education, Youth and Sports of the CR, Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)

• MSM0021622415, plan (intention): Name: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations