| PLÁNKA, Ladislav, Alois NEČAS, Petr GÁL, Alexandra KECOVÁ, Leoš KŘEN and Petr KRUPA. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. ACTA VET. Brno, 2007, vol. 76, No 1, p. 253-263. ISSN 0001-7213. |
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@article{771699,
author = {Plánka, Ladislav and Nečas, Alois and Gál, Petr and Kecová, Alexandra and Křen, Leoš and Krupa, Petr},
article_location = {Brno},
article_number = {1},
keywords = {growth plate injury; physis; growth arrest; limb deformity},
language = {eng},
issn = {0001-7213},
journal = {ACTA VET.},
title = {Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits.},
volume = {76},
year = {2007}
}
TY - JOUR
ID - 771699
AU - Plánka, Ladislav - Nečas, Alois - Gál, Petr - Kecová, Alexandra - Křen, Leoš - Krupa, Petr
PY - 2007
TI - Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits.
JF - ACTA VET.
VL - 76
IS - 1
SP - 253-263
EP - 253-263
SN - 00017213
KW - growth plate injury
KW - physis
KW - growth arrest
KW - limb deformity
N2 - Preventive transplantation of autogenous mesenchymal stem cells into iatrogenically created defect in femoral distal growth plate in rabbit prevented origination of a bone bridge and healed the physeal defect in by hyaline cartilage. Immunofluorescence examination proved that the newly created chondrocytes originated in the growth zone as a result of differentiation of implanted MSCs. Growth of the right femur in the traumatized physis was preserved after transplantation of autogenous MSCs and, compared to the left femur (with physeal defect but without transplanted MSCs), substantial shortening and valgus deformity of the bone did not occur (p=0.018).
ER -
PLÁNKA, Ladislav, Alois NEČAS, Petr GÁL, Alexandra KECOVÁ, Leoš KŘEN and Petr KRUPA. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. \textit{ACTA VET.}. Brno, 2007, vol.~76, No~1, p.~253-263. ISSN~0001-7213.
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