| BÉBAROVÁ, Markéta, Tom 0´HARA, Jan GEELEN, Roselie JONGBLOED, Carl TIMMERMANS, Yvonne ARENS, Luz-Maria RODRIGUEZ, Yoram RUDY a Paul VOLDERS. Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation. American Journal of Physiology - Heart and Circulatory Physiology. 2008, roč. 295, č. 1, s. H48-H58, 10 s. ISSN 0363-6135. |
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@article{772761,
author = {Bébarová, Markéta and 0´Hara, Tom and Geelen, Jan and Jongbloed, Roselie and Timmermans, Carl and Arens, Yvonne and Rodriguez, LuzandMaria and Rudy, Yoram and Volders, Paul},
article_number = {1},
keywords = {Brugada syndrome; mutation; patch clamp; cell lines; arrhythmogenesis},
language = {eng},
issn = {0363-6135},
journal = {American Journal of Physiology - Heart and Circulatory Physiology},
title = {Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation},
volume = {295},
year = {2008}
}
TY - JOUR
ID - 772761
AU - Bébarová, Markéta - 0´Hara, Tom - Geelen, Jan - Jongbloed, Roselie - Timmermans, Carl - Arens, Yvonne - Rodriguez, Luz-Maria - Rudy, Yoram - Volders, Paul
PY - 2008
TI - Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation
JF - American Journal of Physiology - Heart and Circulatory Physiology
VL - 295
IS - 1
SP - H48-H58
EP - H48-H58
SN - 03636135
KW - Brugada syndrome
KW - mutation
KW - patch clamp
KW - cell lines
KW - arrhythmogenesis
N2 - Our data may explain ST-segment elevation on the basis of massive transmural voltage gradients during early repolarization. Reentry-based tachycardia could be evoked during conditions that further exaggerate conduction block in this Brugada phenotype.
ER -
BÉBAROVÁ, Markéta, Tom 0´HARA, Jan GEELEN, Roselie JONGBLOED, Carl TIMMERMANS, Yvonne ARENS, Luz-Maria RODRIGUEZ, Yoram RUDY a Paul VOLDERS. Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation. \textit{American Journal of Physiology - Heart and Circulatory Physiology}. 2008, roč.~295, č.~1, s.~H48-H58, 10 s. ISSN~0363-6135.
|
