Detailed Information on Publication Record

BITTNER, Michal, Klára HILSCHEROVÁ and John, P. GIESY. AhR-ZPROSTŘEDKOVANÁ AKTIVITA HUMINOVÝCH LÁTEK A JEJICH FOTODEGRADAČNÍCH PRODUKTŮ (AhR-MEDIATED ACTIVITY OF HUMIC SUBSTANCES AND THEIR PHOTO-DEGRADATION PRODUCTS). In Bulletin VÚRH Vodňany. Vodňany: Jihočeská univerzita v Českých Budějovicích, Výzkumný ústav rybářský a hydrobiologický ve Vodňanech, 2007, p. 17-22. ISSN 0007-389X.

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Basic information
Original name	AhR-ZPROSTŘEDKOVANÁ AKTIVITA HUMINOVÝCH LÁTEK A JEJICH FOTODEGRADAČNÍCH PRODUKTŮ
Name (in English)	AhR-MEDIATED ACTIVITY OF HUMIC SUBSTANCES AND THEIR PHOTO-DEGRADATION PRODUCTS
Authors	BITTNER, Michal (203 Czech Republic, guarantor), Klára HILSCHEROVÁ (203 Czech Republic) and John, P. GIESY (840 United States of America).
Edition	Vodňany, Bulletin VÚRH Vodňany, p. 17-22, 6 pp. 2007.
Publisher	Jihočeská univerzita v Českých Budějovicích, Výzkumný ústav rybářský a hydrobiologický ve Vodňanech

Other information
Original language	Czech
Type of outcome	Proceedings paper
Field of Study	10511 Environmental sciences
Country of publisher	Czech Republic
Confidentiality degree	is not subject to a state or trade secret
RIV identification code	RIV/00216224:14310/07:00029090
Organization unit	Faculty of Science
ISSN	0007-389X
Keywords in English	Humic Substances; Irradiation; AhR-mediated activity
Tags	AhR-mediated activity, Humic substances, irradiation
Changed by	Changed by: RNDr. Mgr. Michal Bittner, Ph.D., učo 15440. Changed: 27/8/2008 16:05.

Abstract
Humic substances (HS) are ubiquitous in the environment - they constitute the major components of dissolved organic matter in waters and the major part of materials that comprise soil organic matter. However, some studies indicate that HS can induce a direct adverse effect on human health and hormone-like effects on fish, amphibians and invertebrates. HS molecules contain number of aromatic rings and conjugated double bonds - the so called chromophores. That implies irradiation of dissolved HS can lead to a series of photochemical reactions which can act on the HS itself, or on other substances present in aquatic environment along with HS such as e.g. xenobiotics. In this contribution, we summarize our new findings on alteration of AhR-mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation-induced decrease in AhR-mediated activity of dissolved HS are discussed.

Abstract

Humic substances (HS) are ubiquitous in the environment - they constitute the major components of dissolved organic matter in waters and the major part of materials that comprise soil organic matter. However, some studies indicate that HS can induce a direct adverse effect on human health and hormone-like effects on fish, amphibians and invertebrates. HS molecules contain number of aromatic rings and conjugated double bonds - the so called chromophores. That implies irradiation of dissolved HS can lead to a series of photochemical reactions which can act on the HS itself, or on other substances present in aquatic environment along with HS such as e.g. xenobiotics. In this contribution, we summarize our new findings on alteration of AhR-mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation-induced decrease in AhR-mediated activity of dissolved HS are discussed.

Abstract (in English)
Humic substances (HS) are ubiquitous in the environment - they constitute the major components of dissolved organic matter in waters and the major part of materials that comprise soil organic matter. However, some studies indicate that HS can induce a direct adverse effect on human health and hormone-like effects on fish, amphibians and invertebrates. HS molecules contain number of aromatic rings and conjugated double bonds - the so called chromophores. That implies irradiation of dissolved HS can lead to a series of photochemical reactions which can act on the HS itself, or on other substances present in aquatic environment along with HS such as e.g. xenobiotics. In this contribution, we summarize our new findings on alteration of AhR-mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation-induced decrease in AhR-mediated activity of dissolved HS are discussed.

Abstract (in English)

Links
GP525/05/P160, research and development project	Name: In vitro modely pro studium endokrinní disrupce - účinky tradičních a nových typů persistentních organických polutantů
GP525/05/P160, research and development project	Investor: Czech Science Foundation, In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
MSM0021622412, plan (intention)	Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
MSM0021622412, plan (intention)	Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)