BIENERTOVÁ VAŠKŮ, Julie, Lenka ŠPINAROVÁ, Petr BIENERT and Anna VAŠKŮ. Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population. Heart Vessels. Japonsko: Springer Japan, 24/2009, No 2, p. 131-137. ISSN 0910-8327. 2009.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population
Name in Czech Asociace mezi polymorfismy v genech kódujících leptin, leptinový receptor a proopiomelanokortin a chronickým srdečním selháním u České populace
Authors BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor), Lenka ŠPINAROVÁ (203 Czech Republic), Petr BIENERT (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic).
Edition Heart Vessels, Japonsko, Springer Japan, 2009, 0910-8327.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher Japan
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.716
RIV identification code RIV/00216224:14110/09:00033786
Organization unit Faculty of Medicine
UT WoS 000264836000010
Keywords in English Adipokines ; Polymorphisms; Leptin; Leptin receptor; Proopiomelanocortin; Chronic heart failure
Tags adipokines, chronic heart failure, leptin, leptin receptor, polymorphisms, proopiomelanocortin
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Anna Vašků, CSc., učo 122. Changed: 17/6/2009 13:31.
Abstract
Patients with chronic heart failure (CHF) express enhanced catabolic metabolism finally resulting in overall weight loss, whereas adipokines might play a crucial role in signaling among tissues. The role of the polymorphic variants in the genes encoding for adipokines as potential CHF susceptibility genes is unclear. Based on our findings, the LEPR Gln223Arg polymorphism could be considered a disease susceptibility modulating factor both in ischemic heart disease or dilated cardiomyopathy patients.
Abstract (in Czech)
Studie sleduje souvislost mezi geny podílejícími se na kontrole energetické homeostázy organismu a chronickým srdečním selháním v české populaci.
PrintDisplayed: 16/4/2024 19:53