J 2008

Impact of behavioural sensitization and estrogen levels on i.v. self-administration of methamphetamine in rats

KUČEROVÁ, Jana; Dagmar VRŠKOVÁ and Alexandra ŠULCOVÁ

Basic information

Original name

Impact of behavioural sensitization and estrogen levels on i.v. self-administration of methamphetamine in rats

Name in Czech

Vliv sensitizace metamfetaminem a hladin estrogenů na příjem drogy v modelu "i.v. self-administration" u potkana

Authors

Edition

European Neuropsychopharmacology, Amsterdam (The Netherlands), Elsevier, 2008, 0924-977X

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 3.661

Organization unit

Faculty of Medicine

UT WoS

000259593801380

Keywords in English

behavioural sensitization; i.v. self-administration; estrogen; rat
Changed: 29/6/2009 10:35, MVDr. Dagmar Vršková, Ph.D.

Abstract

In the original language

The model of i.v. self-administration of MET (or saline as control) combined with fourteen days of intermittent pretreatment with MET (or saline) was used hypothesizing potential influence of behavioral sensitization to MET on the spontaneous intake in twenty-one i.v. self-administration everyday sessions (120 min.) in male and female ovariectomized rats with and without estrogen substitution.

In Czech

Byl použit model "i.v. self-administration" metamfetaminu (fyziologický roztok jako kontrola) v kombinaci se 14 dní trvající premedimací metamfetaminem k vyvolání behaviorální sensitizace. Byl sledován vliv sensitizace a hormonální hladiny samic na spontánní příjem drogy v modelu "i.v. self-administration".

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.