Do the female hormones and repeated administration of methamphetamine affect the spontaneous i.v. self-administration of the drug in rats?

KUČEROVÁ, Jana, Dagmar VRŠKOVÁ and Alexandra ŠULCOVÁ. Do the female hormones and repeated administration of methamphetamine affect the spontaneous i.v. self-administration of the drug in rats? Prague medical report : interdisciplinary biomedical journal of the First Faculty of Medicine, Charles University in Prague. Prague: Karolinum, 2008, vol. 109, Suppl., p. 71-73. ISSN 1214-6994.

Basic information

• Original name: Do the female hormones and repeated administration of methamphetamine affect the spontaneous i.v. self-administration of the drug in rats?
• Name in Czech: Ovlivňují samičí pohlavní hormony a opakované podání metamfetaminu příjem drogy v modelu "i.v. self-administration" u potkana?
• Authors: KUČEROVÁ, Jana (203 Czech Republic, guarantor), Dagmar VRŠKOVÁ (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic).
• Edition: Prague medical report : interdisciplinary biomedical journal of the First Faculty of Medicine, Charles University in Prague. Prague, Karolinum, 2008, 1214-6994.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30104 Pharmacology and pharmacy
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/08:00026365
• Organization unit: Faculty of Medicine
• Keywords in English: behavioural sensitization; i.v. self-administration; estrogen; rat
• Tags: behavioural sensitization, estrogen, i.v. self-administration, rat
• Tags: International impact

Abstract

The model of i.v. self-administration of MET (or saline as control) combined with fourteen days (14 D) of intermittent pretreatment with MET (or saline) was used hypothesizing potential influence of behavioral sensitization to MET on the spontaneous intake in twenty-one i.v. self-administration everyday sessions (120 min.) in male and female ovariectomized rats with and without estrogen substitution.

Abstract (in Czech)

Byl použit model "i.v. self-administration" metamfetaminu (fyziologický roztok jako kontrola) v kombinaci se 14 dní trvající premedimací metamfetaminem k vyvolání behaviorální sensitizace. Byl sledován vliv sensitizace a hormonální hladiny samic na spontánní příjem drogy v modelu "i.v. self-administration".

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.