Diagnosis and treatment of malignant lymphomas in pregnancy and
lactation, our own experiences

a 2008

Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences

ŠMARDOVÁ, Lenka, Zdeněk KRÁL, Ingrid VÁŠOVÁ, Milan NAVRÁTIL, Martin HUSER et. al.

Basic information

Original name

Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences

Name in Czech

Diagnostika a léčba maligních lymfomů v době těhotenství a laktace, vlastní zkušenosti

Authors

ŠMARDOVÁ, Lenka, Zdeněk KRÁL, Ingrid VÁŠOVÁ, Milan NAVRÁTIL, Martin HUSER, Martina TOŠKOVÁ, Jiří MAYER and Jiří VORLÍČEK

Edition

Pavia, Itálie, Haematologica/The Hematology Journal. p. 561-561, 1 pp. 2008

Publisher

EHA Executive Office, Rotterdam, Nizozemí

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Denmark

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 5.978

Organization unit

Faculty of Medicine

ISSN

UT WoS

000263430201723

Keywords in English

lymphoma; pregnancy; chemotherapy

Abstract

ORIG CZ

V originále

Background: The lymphomas represent the fourth most frequent malignancy diagnosed during pregnancy, occuring in approximately 1:6000 deliveries. Considerably more often is a diagnosis of the Hodgkins lymphoma, possibly because of the natural incidence of this disease in the reproductive age of the patients. Material and methods: Since 2001 there were diagnosed 17 patients with a lymphoma during pregnancy or lactation at our clinic. The median age of the patients was 27 years. The histological types of lymphomas were in most of the cases Hodgkins lymphoma (N=13), then diffuse large B-cell lymphoma (N=3) and MALT lymphoma of a eye-lid (N=1). The diagnosis was determined in the 1st (N=2), the 2nd (N=4) and the 3rd trimester (N=4) of pregnancy, at the other 7 patients during lactation (4 of them had a fever or swelling nodes aready during the pregnancy). In most of the cases the patients were diagnosed at clinical stage II. Results: 3 of the patients diagnosed during the 1st and the 2nd trimester had an abortion on their own request, 11 patients gave birth to a healthy child naturally (N=7) or by Caesarean section (N=4). In three cases the disease was diagnosed in a critical state of the patients (superior vena cava syndrome or an obstructive ileus), requiring an abortion because of the medical indication of the mother. In the therapeutic plan a histological type of the lymphoma and a clinical stage of the disease were respected. All the patients initiated the treatment after the ending of the pregnancy. The complete remission was achieved at all the patients. 4 of the patients gave birth to a healthy child after the completion of the treatment, the other 2 are currently pregnant. Conclusions: The cases of the diagnosis of the malignant lymphoma during pregnancy are increasing together with the tendency to the family planning in the older age of the mother. However, the pregnancy doesnt affect the overall survival as well as it doesnt influence the prognosis of the disease negatively. The diagnosis of the malignant lymphoma during pregnancy requires a specific and individual attitude while planning the staging examinations and the therapeutical programme has to take into account the wish of the patient.

In Czech

Diagnostika a léčba maligních lymfomů v době těhotenství a laktace, vlastní zkušenosti.

Citovat

ŠMARDOVÁ, Lenka, Zdeněk KRÁL, Ingrid VÁŠOVÁ, Milan NAVRÁTIL, Martin HUSER, Martina TOŠKOVÁ, Jiří MAYER and Jiří VORLÍČEK. Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences. In Haematologica/The Hematology Journal. Pavia, Itálie: EHA Executive Office, Rotterdam, Nizozemí, 2008, p. 561-561. ISSN 0390-6078.

@proceedings{778640,
   author = {Šmardová, Lenka and Král, Zdeněk and Vášová, Ingrid and Navrátil, Milan and Huser, Martin and Tošková, Martina and Mayer, Jiří and Vorlíček, Jiří},
   address = {Pavia, Itálie},
   booktitle = {Haematologica/The Hematology Journal.},
   keywords = {lymphoma; pregnancy; chemotherapy},
   language = {eng},
   location = {Pavia, Itálie},
   pages = {561-561},
   publisher = {EHA Executive Office, Rotterdam, Nizozemí},
   title = {Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences},
   year = {2008}
}

TY  - CONF
ID  - 778640
AU  - Šmardová, Lenka - Král, Zdeněk - Vášová, Ingrid - Navrátil, Milan - Huser, Martin - Tošková, Martina - Mayer, Jiří - Vorlíček, Jiří
PY  - 2008
TI  - Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences
PB  - EHA Executive Office, Rotterdam, Nizozemí
CY  - Pavia, Itálie
KW  - lymphoma
KW  - pregnancy
KW  - chemotherapy
N2  - Background: The lymphomas represent the fourth most frequent malignancy diagnosed during pregnancy, occuring in approximately 1:6000 deliveries. Considerably more often is a diagnosis of the Hodgkins lymphoma, possibly because of the natural incidence of this disease in the reproductive age of the patients. Material and methods: Since 2001 there were diagnosed 17 patients with a lymphoma during pregnancy or lactation at our clinic. The median age of the patients was 27 years. The histological types of lymphomas were in most of the cases Hodgkins lymphoma (N=13), then diffuse large B-cell lymphoma (N=3) and MALT lymphoma of a eye-lid (N=1). The diagnosis was determined in the 1st (N=2), the 2nd (N=4) and the 3rd trimester (N=4) of pregnancy, at the other 7 patients during lactation (4 of them had a fever or swelling nodes aready during the pregnancy). In most of the cases the patients were diagnosed at clinical stage II. Results: 3 of the patients diagnosed during the 1st and the 2nd trimester had an abortion on their own request, 11 patients gave birth to a healthy child naturally (N=7) or by Caesarean section (N=4). In three cases the disease was diagnosed in a critical state of the patients (superior vena cava syndrome or an obstructive ileus), requiring an abortion because of the medical indication of the mother. In the therapeutic plan a histological type of the lymphoma and a clinical stage of the disease were respected. All the patients initiated the treatment after the ending of the pregnancy. The complete remission was achieved at all the patients. 4 of the patients gave birth to a healthy child after the completion of the treatment, the other 2 are currently pregnant. Conclusions: The cases of the diagnosis of the malignant lymphoma during pregnancy are increasing together with the tendency to the family planning in the older age of the mother. However, the pregnancy doesnt affect the overall survival as well as it doesnt influence the prognosis of the disease negatively. The diagnosis of the malignant lymphoma during pregnancy requires a specific and individual attitude while planning the staging examinations and the therapeutical programme has to take into account the wish of the patient.
ER  -

ŠMARDOVÁ, Lenka, Zdeněk KRÁL, Ingrid VÁŠOVÁ, Milan NAVRÁTIL, Martin HUSER, Martina TOŠKOVÁ, Jiří MAYER and Jiří VORLÍČEK. Diagnosis and treatment of malignant lymphomas in pregnancy and lactation, our own experiences. In \textit{Haematologica/The Hematology Journal.}. Pavia, Itálie: EHA Executive Office, Rotterdam, Nizozemí, 2008, p.~561-561. ISSN~0390-6078.

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