D 2008

Two common polymorphisms within the adiponectin gene are associated with food preferences in extremely obese Czech individuals

BIENERTOVÁ VAŠKŮ, Julie, Martin FOREJT, Josef TOMANDL, Petr BIENERT, Anna VAŠKŮ et. al.

Basic information

Original name

Two common polymorphisms within the adiponectin gene are associated with food preferences in extremely obese Czech individuals

Name in Czech

Dva v populaci četné polymorfismy v genu pro adiponektin jsou asociovány s potravními preferencemi české extrémně obézní populace

Edition

Karlovy Vary, 1st Central European Congress on Obesity, p. 47-47, 1 pp. 2008

Publisher

European Association for the Study of Obesity

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

Genetics and molecular biology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

ISBN

978-80-254-2733-0

Keywords in English

adiponectin; polymorphism; extreme obesity; food preferences

Tags

International impact, Reviewed
Změněno: 3/12/2008 20:32, doc. RNDr. Josef Tomandl, Ph.D.

Abstract

V originále

Objective: Considering the pivotal role of adiponectin in white adipose tissue metabolism and signaling, we assessed whether the 45T/G and 94T/G polymorphisms within the adiponectin gene influence the food preferences along with basic anthropometric characteristics in the Czech extremely obese population. Conclusions: Both examined polymorphism were significantly associated with various parametres of food intake, above all the total and relative intake of carbohydrates, which could provide possible explanation for the documented prodiabetogenic effects of these polymorphisms. The obtained results well fit into a framework for food intake regulation in relation to adiponectin role and could provide possible targets for further nutrigenomical research and intervention focused on the food preferences.

In Czech

Na základě získaných výsledků se zdá, že oba sledované polymorfismy přímo ovlivňují potravní preference obézních jedinců, zvláště obsah karbohydrátů v potravě, což je zajímavé z hlediska dokumentovaného prodiabetogenního efektu těchto polymorfismů.