2008
C-13 Relaxation Studies of RNA Dynamics: Challenges and Solutions
KADEŘÁVEK, Pavel and Radovan FIALABasic information
Original name
C-13 Relaxation Studies of RNA Dynamics: Challenges and Solutions
Name in Czech
Studium dynamiky RNA pomocí relaxace C-13: Problémy a jejich řešení
Authors
Edition
San Diego, XXIII International Conference on Magnetic Resonance in Biological Systems, p. 117-117, 2008
Publisher
ICMRBS
Other information
Language
English
Type of outcome
Proceedings paper
Field of Study
10610 Biophysics
Country of publisher
United States of America
Confidentiality degree
is not subject to a state or trade secret
Organization unit
Faculty of Science
Keywords in English
NMR; nucleic acids;RNA;dynamics
Tags
Tags
International impact
Changed: 11/12/2008 13:16, doc. RNDr. Radovan Fiala, CSc.
V originále
NMR relaxation experiments provide a way of monitoring molecular dynamics with atomic resolution. However, the measurement of 13C relaxation rates and their interpretation faces serious challenges. We have modified the Model-Free procedure to explicitly take into account asymmetric character of the carbon chemical shielding tensors and the effect of neighboring nuclei. The extended version of the Model-Free analysis generally produces more realistic values of the order parameter.
In Czech
NMR relaxation experiments provide a way of monitoring molecular dynamics with atomic resolution. However, the measurement of 13C relaxation rates and their interpretation faces serious challenges. We have modified the Model-Free procedure to explicitly take into account asymmetric character of the carbon chemical shielding tensors and the effect of neighboring nuclei. The extended version of the Model-Free analysis generally produces more realistic values of the order parameter.
Links
| LC06030, research and development project |
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| MSM0021622413, plan (intention) |
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