Detailed Information on Publication Record
2008
C-13 Relaxation Studies of RNA Dynamics: Challenges and Solutions
KADEŘÁVEK, Pavel and Radovan FIALABasic information
Original name
C-13 Relaxation Studies of RNA Dynamics: Challenges and Solutions
Name in Czech
Studium dynamiky RNA pomocí relaxace C-13: Problémy a jejich řešení
Authors
Edition
San Diego, XXIII International Conference on Magnetic Resonance in Biological Systems, p. 117-117, 2008
Publisher
ICMRBS
Other information
Language
English
Type of outcome
Stať ve sborníku
Field of Study
10610 Biophysics
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Organization unit
Faculty of Science
Keywords in English
NMR; nucleic acids;RNA;dynamics
Tags
Tags
International impact
Změněno: 11/12/2008 13:16, doc. RNDr. Radovan Fiala, CSc.
V originále
NMR relaxation experiments provide a way of monitoring molecular dynamics with atomic resolution. However, the measurement of 13C relaxation rates and their interpretation faces serious challenges. We have modified the Model-Free procedure to explicitly take into account asymmetric character of the carbon chemical shielding tensors and the effect of neighboring nuclei. The extended version of the Model-Free analysis generally produces more realistic values of the order parameter.
In Czech
NMR relaxation experiments provide a way of monitoring molecular dynamics with atomic resolution. However, the measurement of 13C relaxation rates and their interpretation faces serious challenges. We have modified the Model-Free procedure to explicitly take into account asymmetric character of the carbon chemical shielding tensors and the effect of neighboring nuclei. The extended version of the Model-Free analysis generally produces more realistic values of the order parameter.
Links
| LC06030, research and development project |
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| MSM0021622413, plan (intention) |
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