J 2008

Sleep deprivation therapy

ŠVESTKA, Jaromír

Basic information

Original name

Sleep deprivation therapy

Name in Czech

Léčba spánkové deprivace

Authors

ŠVESTKA, Jaromír

Edition

NEUROENDOCRINOLOGY LETTERS, Sweden, Neuro Endocrinology Letters ISSN 0172–780X, 2008, 0172-780X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Sweden

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.359

Organization unit

Faculty of Medicine

UT WoS

000264574200005

Keywords in English

sleep; deprivation; pharmacotherapy; therapy
Změněno: 30/6/2009 09:40, prof. MUDr. Eva Češková, CSc.

Abstract

V originále

Sleep deprivation is a useful therapeutic option in the treatment of depressive disorders, especially in pharmacoresistant disorders. Its therapeutic efficacy in other indications has not, however, been confirmed. According to current knowledge, application of sleep therapy requires concomitant therapy to prevent early relapses of depression. Total sleep deprivation is the classic variant of its clinical use. Partial sleep deprivation has a somewhat less pronounced antidepressant effect, and the duration of sleep deprivation rather than application timing determines its therapeutic effect. The most reliable predictors of sleep deprivation efficacy are marked diurnal fluctuations of depressive mood, patient locomotor activity, and limbic hyperactivity in the central nervous system. The mechanism of the antidepressant effect of sleep deprivation remains unknown.

In Czech

Článek popisuje různé způsoby a výsledky při léčbě spánkové deprivace - zvláště u pacientů s depresí.