| MICKOVÁ, A., K. TOMÁNKOVÁ, H. KOLÁŘOVÁ, R. BAJGAR, P. KOLÁŘ, Pavel ŠUNKA, P. PLENCNER, M. JAKUBOVÁ, J. BENEŠ, L. KOLÁČNÁ, Ladislav PLÁNKA, Alois NEČAS and E. AMLER. Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects. Acta Veterinaria. Brno, 2008, vol. 77, No 2, p. 285-290, 5 pp. ISSN 0001-7213. |
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@article{800254,
author = {Micková, A. and Tománková, K. and Kolářová, H. and Bajgar, R. and Kolář, P. and Šunka, Pavel and Plencner, P. and Jakubová, M. and Beneš, J. and Koláčná, L. and Plánka, Ladislav and Nečas, Alois and Amler, E.},
article_location = {Brno},
article_number = {2},
keywords = {Liposome;controlled drug delivery;ultrasound shock-wave;fluorescence},
language = {eng},
issn = {0001-7213},
journal = {Acta Veterinaria},
title = {Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects},
volume = {77},
year = {2008}
}
TY - JOUR
ID - 800254
AU - Micková, A. - Tománková, K. - Kolářová, H. - Bajgar, R. - Kolář, P. - Šunka, Pavel - Plencner, P. - Jakubová, M. - Beneš, J. - Koláčná, L. - Plánka, Ladislav - Nečas, Alois - Amler, E.
PY - 2008
TI - Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects
JF - Acta Veterinaria
VL - 77
IS - 2
SP - 285-290
EP - 285-290
SN - 00017213
KW - Liposome;controlled drug delivery;ultrasound shock-wave;fluorescence
N2 - A short liposome exposure to ultrasonic waves with the intensity of I = 2 W/cm2 at frequency f = 1 MHz was found to be a sufficient tool for liposome opening. In addition, shock-wave proved to be sufficient also for liposome content release. Both methods are useful tools to be used as control mechanisms for drug delivery systems based on liposomes. However, due to better focusing and low non-thermal side effects, shock-waves probably have a markedly higher potential for successful use.
ER -
MICKOVÁ, A., K. TOMÁNKOVÁ, H. KOLÁŘOVÁ, R. BAJGAR, P. KOLÁŘ, Pavel ŠUNKA, P. PLENCNER, M. JAKUBOVÁ, J. BENEŠ, L. KOLÁČNÁ, Ladislav PLÁNKA, Alois NEČAS and E. AMLER. Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects. \textit{Acta Veterinaria}. Brno, 2008, vol.~77, No~2, p.~285-290, 5 pp. ISSN~0001-7213.
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