Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug
Delivery System for Possible Use in Scaffold Implanted to
Animals with Iatrogenic Articular Cartilage Defects

J 2008

Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects

MICKOVÁ, A., K. TOMÁNKOVÁ, H. KOLÁŘOVÁ, R. BAJGAR, P. KOLÁŘ et. al.

Basic information

Original name

Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects

Name in Czech

Ultrazvukové vlny jako kontrolní mechanismus pro uvolňování účinných látek z lipozomů použité u skafoldů implantovaných do iatrogenního defektu kloubní chrupavky

Authors

MICKOVÁ, A. (203 Czech Republic), K. TOMÁNKOVÁ (203 Czech Republic), H. KOLÁŘOVÁ (203 Czech Republic), R. BAJGAR (203 Czech Republic), P. KOLÁŘ (203 Czech Republic), Pavel ŠUNKA (203 Czech Republic), P. PLENCNER (203 Czech Republic), M. JAKUBOVÁ (203 Czech Republic), J. BENEŠ (203 Czech Republic), L. KOLÁČNÁ (203 Czech Republic), Ladislav PLÁNKA (203 Czech Republic, guarantor), Alois NEČAS (203 Czech Republic) and E. AMLER (203 Czech Republic)

Edition

Acta Veterinaria, Brno, 2008, 0001-7213

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30211 Orthopaedics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.395

RIV identification code

RIV/00216224:14110/08:00027073

Organization unit

Faculty of Medicine

UT WoS

000257226400019

Keywords in English

Liposome;controlled drug delivery;ultrasound shock-wave;fluorescence

Abstract

ORIG CZ

V originále

A short liposome exposure to ultrasonic waves with the intensity of I = 2 W/cm2 at frequency f = 1 MHz was found to be a sufficient tool for liposome opening. In addition, shock-wave proved to be sufficient also for liposome content release. Both methods are useful tools to be used as control mechanisms for drug delivery systems based on liposomes. However, due to better focusing and low non-thermal side effects, shock-waves probably have a markedly higher potential for successful use.

In Czech

Krátkodobá expozice UZ vln o intenzitě 2 W/cm2 a frekvenci 1 MHz byla pozorována jako dostatečná pro otevření lopozomů, stejně jako šoková stimulace UZ vlnami. Obě metody mohou sloužit jako kontrolní mechanismus pro uvolňování účinných látek z lipozomů použité u skafoldů implantovaných do iatrogenního defektu kloubní chrupavky

Citovat

MICKOVÁ, A., K. TOMÁNKOVÁ, H. KOLÁŘOVÁ, R. BAJGAR, P. KOLÁŘ, Pavel ŠUNKA, P. PLENCNER, M. JAKUBOVÁ, J. BENEŠ, L. KOLÁČNÁ, Ladislav PLÁNKA, Alois NEČAS and E. AMLER. Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects. Acta Veterinaria. Brno, 2008, vol. 77, No 2, p. 285-290, 5 pp. ISSN 0001-7213.

@article{800254,
   author = {Micková, A. and Tománková, K. and Kolářová, H. and Bajgar, R. and Kolář, P. and Šunka, Pavel and Plencner, P. and Jakubová, M. and Beneš, J. and Koláčná, L. and Plánka, Ladislav and Nečas, Alois and Amler, E.},
   article_location = {Brno},
   article_number = {2},
   keywords = {Liposome;controlled drug delivery;ultrasound shock-wave;fluorescence},
   language = {eng},
   issn = {0001-7213},
   journal = {Acta Veterinaria},
   title = {Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects},
   volume = {77},
   year = {2008}
}

TY  - JOUR
ID  - 800254
AU  - Micková, A. - Tománková, K. - Kolářová, H. - Bajgar, R. - Kolář, P. - Šunka, Pavel - Plencner, P. - Jakubová, M. - Beneš, J. - Koláčná, L. - Plánka, Ladislav - Nečas, Alois - Amler, E.
PY  - 2008
TI  - Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects
JF  - Acta Veterinaria
VL  - 77
IS  - 2
SP  - 285-290
EP  - 285-290
SN  - 00017213
KW  - Liposome;controlled drug delivery;ultrasound shock-wave;fluorescence
N2  - A short liposome exposure to ultrasonic waves with the intensity of I = 2 W/cm2 at frequency f = 1 MHz was found to be a sufficient tool for liposome opening. In addition, shock-wave proved to be sufficient also for liposome content release. Both methods are useful tools to be used as control mechanisms for drug delivery systems based on liposomes. However, due to better focusing and low non-thermal side effects, shock-waves probably have a markedly higher potential for successful use.
ER  -

MICKOVÁ, A., K. TOMÁNKOVÁ, H. KOLÁŘOVÁ, R. BAJGAR, P. KOLÁŘ, Pavel ŠUNKA, P. PLENCNER, M. JAKUBOVÁ, J. BENEŠ, L. KOLÁČNÁ, Ladislav PLÁNKA, Alois NEČAS and E. AMLER. Ultrasonic Shock-Wave as a Control Mechanism for Liposome Drug Delivery System for Possible Use in Scaffold Implanted to Animals with Iatrogenic Articular Cartilage Defects. \textit{Acta Veterinaria}. Brno, 2008, vol.~77, No~2, p.~285-290, 5 pp. ISSN~0001-7213.

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