Other formats:
BibTeX
LaTeX
RIS
@article{807337, author = {Tatsunami, Shinobu and Mimaya, Junichi and Shirata, Akira and Zelinka, Jiří and Horová, Ivanka and Hanai, Jugo and Nishina, Yukata and Ohira, Katsumi and Taki, Masashi}, article_location = {Japonsko}, article_number = {3}, keywords = {Hemophiliacs; Coagulation disorders; HIV; HCV; Survival; Surveillance}, language = {eng}, issn = {0925-5710}, journal = {International Journal of Hematology}, title = {Current status of Japanese HIV-infected patients with coagulation disorders : coinfection with both HIV and HCV}, url = {http://springerlink.com/content/yx74v732v6843j2g/}, volume = {88}, year = {2008} }
TY - JOUR ID - 807337 AU - Tatsunami, Shinobu - Mimaya, Junichi - Shirata, Akira - Zelinka, Jiří - Horová, Ivanka - Hanai, Jugo - Nishina, Yukata - Ohira, Katsumi - Taki, Masashi PY - 2008 TI - Current status of Japanese HIV-infected patients with coagulation disorders : coinfection with both HIV and HCV JF - International Journal of Hematology VL - 88 IS - 3 SP - 304-310 EP - 304-310 PB - Springer SN - 09255710 KW - Hemophiliacs KW - Coagulation disorders KW - HIV KW - HCV KW - Survival KW - Surveillance UR - http://springerlink.com/content/yx74v732v6843j2g/ N2 - We herein report on the current status of Japanese HIV-positive patients with coagulation disorders, primarily hemophilia, based on the national survey of 31 May 2006. The total number of registered patients was 1,431 (Hemophilia A 1,086; Hemophilia B 325; von Willebrand disease 8; others 12), and 604 of these patients were deceased by 31 May 2006. The survival rate after the beginning of 1983 was evaluated by the Kaplan-Meier method. The total number of surviving patients was 827, and the survival rate on 31 May 2006 was 55.7 +- 1.4%. Among the 827 surviving patients, HCV antibody was observed in 740, was negative in 16, and was not reported in 71 patients. Thus, the prevalence of HCV infection was 98% in the surviving patients based on the presence of HCV antibody. Among the 604 deceased patients, liver disease was reported as a cause of death in 149 cases (25%), and infection with HCV was reported as the possible cause of liver disease in 120 cases (20%). After 1997, 63 cases among the subtotal of 148 deaths had critical hepatic disease that originated from HCV infection, which accounted for 43% of the subtotal. The cumulative rate of patients who received interferon therapy was 32%. Interferon therapy should be prescribed more frequently to HIV-positive patients with coagulation disorders in order to realize the survival benefits, although clinicians should be aware of side effects and toxicities. ER -
TATSUNAMI, Shinobu, Junichi MIMAYA, Akira SHIRATA, Jiří ZELINKA, Ivanka HOROVÁ, Jugo HANAI, Yukata NISHINA, Katsumi OHIRA and Masashi TAKI. Current status of Japanese HIV-infected patients with coagulation disorders : coinfection with both HIV and HCV. \textit{International Journal of Hematology}. Japonsko: Springer, 2008, vol.~88, No~3, p.~304-310. ISSN~0925-5710.
|