Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution

KUČEROVÁ, Jana and Alexandra ŠULCOVÁ. Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution. Activitas Nervosa Superior. Prague: Neurosciencia and NC Publishing, 2008, vol. 50, 1-2, p. 18-19. ISSN 1802-9698.

Basic information

• Original name: Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution
• Name in Czech: Vliv behaviorální sensitizace k extázi na chování myších samců a ovariektomovaných samic s a bez substituce estrogenu
• Authors: KUČEROVÁ, Jana (203 Czech Republic, guarantor) and Alexandra ŠULCOVÁ (203 Czech Republic).
• Edition: Activitas Nervosa Superior, Prague, Neurosciencia and NC Publishing, 2008, 1802-9698.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30104 Pharmacology and pharmacy
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/08:00027315
• Organization unit: Faculty of Medicine
• Keywords in English: behavioural sensitization; ecstasy; mice; open-field; gender differences
• Tags: behavioural sensitization, ecstasy, gender differences, mice, open-field
• Tags: International impact, Reviewed

Abstract

Repeated administration of ecstasy is known to provoke behavioural sensitization to its effects. This experriment was designed to examine possible gender differences in MDMA-induced behavioral sensitization.

Abstract (in Czech)

Opakované podání extáze vyvolává behaviorální sensitizaci. Tento fenomén se projevuje u samců odlišně než u samic (Izthak, 2004). Proto byl experiment zaměřen na detekci mezipohlavních rozdílů u myší. Byly testovány tři skupiny: samci a ovariektomované samice s a bez substituce přirozeného estrogenu. Hodnocena byla lokomotorická aktivita testem otevřeného pole.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.