Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution

KUČEROVÁ, Jana and Alexandra ŠULCOVÁ. Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution. Activitas Nervosa Superior. Prague: Neurosciencia and NC Publishing, 2008, vol. 50, 1-2, p. 18-19. ISSN 1802-9698.

Basic information

Original name

Comparison of behavioral sensitization to ecstasy in mouse males and ovariectomized females with and without estrogen substitution

Name in Czech

Vliv behaviorální sensitizace k extázi na chování myších samců a ovariektomovaných samic s a bez substituce estrogenu

Authors

KUČEROVÁ, Jana (203 Czech Republic, guarantor) and Alexandra ŠULCOVÁ (203 Czech Republic)

Edition

Activitas Nervosa Superior, Prague, Neurosciencia and NC Publishing, 2008, 1802-9698

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/08:00027315

Organization unit

Faculty of Medicine

Keywords in English

behavioural sensitization; ecstasy; mice; open-field; gender differences

Tags

behavioural sensitization, ecstasy, gender differences, mice, open-field

Tags

International impact, Reviewed

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Abstract

V originále

Repeated administration of ecstasy is known to provoke behavioural sensitization to its effects. This experriment was designed to examine possible gender differences in MDMA-induced behavioral sensitization.

In Czech

Opakované podání extáze vyvolává behaviorální sensitizaci. Tento fenomén se projevuje u samců odlišně než u samic (Izthak, 2004). Proto byl experiment zaměřen na detekci mezipohlavních rozdílů u myší. Byly testovány tři skupiny: samci a ovariektomované samice s a bez substituce přirozeného estrogenu. Hodnocena byla lokomotorická aktivita testem otevřeného pole.

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Links

MSM0021622404, plan (intention)

Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.