VESELSKÁ, Renata, Markéta HERMANOVÁ, Tomáš LOJA, Petr CHLAPEK, Iva ZAMBO, Karel VESELÝ, Karel ZITTERBART and Jaroslav ŠTĚRBA. Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer. 2008, vol. 8, No 300, 8 pp. ISSN 1471-2407.
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Basic information
Original name Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines.
Name in Czech Exprese nestinu v osteosarkomech a derivování nestin/CD133 pozitivních osteosarkomových buněčných linií.
Authors VESELSKÁ, Renata (203 Czech Republic, guarantor), Markéta HERMANOVÁ (203 Czech Republic), Tomáš LOJA (703 Slovakia), Petr CHLAPEK (203 Czech Republic), Iva ZAMBO (203 Czech Republic), Karel VESELÝ (203 Czech Republic), Karel ZITTERBART (203 Czech Republic) and Jaroslav ŠTĚRBA (203 Czech Republic).
Edition BMC Cancer, 2008, 1471-2407.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.087
RIV identification code RIV/00216224:14310/08:00025211
Organization unit Faculty of Science
UT WoS 000261555300002
Keywords in English nestin; CD133; intermediate filaments; osteosarcoma; immunocytochemistry; immunohistochemistry; cancer stem cells
Tags cancer stem cells, CD133, immunocytochemistry, Immunohistochemistry, intermediate filaments, nestin, osteosarcoma
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Renata Veselská, Ph.D., M.Sc., učo 1260. Changed: 18/6/2009 12:40.
Abstract
Immunohistochemical and immunocytochemical methods demonstrate the expression of nestin, the intermediate filament protein class VI, in osteosarcomas. Osteosarcoma cell lines showing nestin+/CD133+ phenotype were successfully derived from these tumors.
Abstract (in Czech)
S využitím imunohistochemických a imunocytochemických metod byla prokázána exprese nestinu (proteinu intermediárních filament třídy VI) v osteosarkomech. Z těchto nádorů byly úspěšně derivovány buněčné linie s fenotypem nestin+/CD133+.
Links
GD204/08/H054, research and development projectName: Molekulární mechanismy proliferace a diferenciace buněk
Investor: Czech Science Foundation, Molecular mechanisms of the cell proliferation and differentiation
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
NR9125, research and development projectName: Diagnostický a prediktivní význam molekulárně cytogenetických markerů u embryonálních nádorů dětského věku.
Investor: Ministry of Health of the CR
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