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@article{819321,
author = {Šulcová, Alexandra and Pistovčáková, Jana},
article_location = {Cambridge, U.K.},
article_number = {Suppl 1},
keywords = {animal; models; depression; antidepressants},
language = {eng},
issn = {1461-1457},
journal = {The International Journal of Neuropsychopharmacology},
title = {Animal behavioural models of depression},
volume = {11},
year = {2008}
}
TY - JOUR
ID - 819321
AU - Šulcová, Alexandra - Pistovčáková, Jana
PY - 2008
TI - Animal behavioural models of depression
JF - The International Journal of Neuropsychopharmacology
VL - 11
IS - Suppl 1
SP - 69
EP - 69
PB - Cambridge University Press
SN - 14611457
KW - animal
KW - models
KW - depression
KW - antidepressants
N2 - The original results presented: a) At the doses used none of drugs tested for their potential antidepressant-like effects (e.g. felbamate, tiagabine, sertindole, amisulpride) changed locomotor behaviour of sham-operated rats, however they inhibited locomotor hyperactivity in the open field test in OB rats. b) Compared to control individuals the group-housed mice repeatedly defeated on interaction with aggressive singly-housed male mouse exhibit significantly higher depression of ambulation in the open field test. This was normalized by clinically proven (e.g. citalopram, valproate) as well as potential antidepressants (e.g. felbamate, rimonabant).
ER -
ŠULCOVÁ, Alexandra and Jana PISTOVČÁKOVÁ. Animal behavioural models of depression. \textit{The International Journal of Neuropsychopharmacology}. Cambridge, U.K.: Cambridge University Press, 2008, vol.~11, Suppl 1, p.~69. ISSN~1461-1457.
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