BRYJA, Vítězslav, Emma R. ANDERSSON, Alexandra SCHAMBONY, Milan ESNER, Lenka BRYJOVÁ, Kristin K. BIRIS, Anita C. HALL, Bianca KRAFT, Lukáš ČAJÁNEK, Terry P. YAMAGUCHI, Margaret BUCKINGHAM and Ernest ARENAS. The Extracellular Domain of Lrp5/6 Inhibits Non-Canonical Wnt Signaling in vivo. : Molecular Biology of the Cell. 2008, vol. 20, No 3, 13 pp. ISSN 1059-1524. |
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@article{819432, author = {Bryja, Vítězslav and Andersson, Emma R. and Schambony, Alexandra and Esner, Milan and Bryjová, Lenka and Biris, Kristin K. and Hall, Anita C. and Kraft, Bianca and Čajánek, Lukáš and Yamaguchi, Terry P. and Buckingham, Margaret and Arenas, Ernest}, article_number = {3}, keywords = {non-canonical Wnt signalling; Lrp5/6; mouse; Xenopus}, language = {eng}, issn = {1059-1524}, journal = {: Molecular Biology of the Cell}, title = {The Extracellular Domain of Lrp5/6 Inhibits Non-Canonical Wnt Signaling in vivo.}, volume = {20}, year = {2008} }
TY - JOUR ID - 819432 AU - Bryja, Vítězslav - Andersson, Emma R. - Schambony, Alexandra - Esner, Milan - Bryjová, Lenka - Biris, Kristin K. - Hall, Anita C. - Kraft, Bianca - Čajánek, Lukáš - Yamaguchi, Terry P. - Buckingham, Margaret - Arenas, Ernest PY - 2008 TI - The Extracellular Domain of Lrp5/6 Inhibits Non-Canonical Wnt Signaling in vivo. JF - : Molecular Biology of the Cell VL - 20 IS - 3 SN - 10591524 KW - non-canonical Wnt signalling KW - Lrp5/6 KW - mouse KW - Xenopus N2 - Lrp5/6 are crucial coreceptors for Wnt/beta-catenin signaling, a pathway biochemically distinct from noncanonical Wnt signaling pathways. Here, we examined the possible participation of Lrp5/6 in noncanonical Wnt signaling using biochemical approach, and mouse and Xenopus in vivo models. We provide evidence that the extracellular domains of Lrp5/6 behave as physiologically relevant inhibitors of noncanonical Wnt signaling during Xenopus and mouse development in vivo. ER -
BRYJA, Vítězslav, Emma R. ANDERSSON, Alexandra SCHAMBONY, Milan ESNER, Lenka BRYJOVÁ, Kristin K. BIRIS, Anita C. HALL, Bianca KRAFT, Lukáš ČAJÁNEK, Terry P. YAMAGUCHI, Margaret BUCKINGHAM and Ernest ARENAS. The Extracellular Domain of Lrp5/6 Inhibits Non-Canonical Wnt Signaling in vivo. \textit{: Molecular Biology of the Cell}. 2008, vol.~20, No~3, 13 pp. ISSN~1059-1524.
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