Detection and treatment of molecular relapse in acute myeloid
leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI
mutation. Frequent quantitative monitoring of molecular markers
in different compartments and correlation with WT1 gene
expression.

J 2008

Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.

DOUBEK, Michael, Ivo PALÁSEK, Z. POSPÍŠIL, S. STRUNCOVÁ, Dana DVOŘÁKOVÁ et. al.

Basic information

Original name

Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.

Name in Czech

Detekce a léčba molekulárního relapsu při akutní myeloidní leukemii s genovými transkripty RUNXa, CBFB, MLL

Authors

DOUBEK, Michael, Ivo PALÁSEK, Z. POSPÍŠIL, S. STRUNCOVÁ, Dana DVOŘÁKOVÁ, M. BORSKÝ, Martin KLABUSAY, Y. BRYCHTOVÁ, Marta KREJČÍ and Jiří MAYER

Edition

Annals of Hematology, Springer, 2008, 0939-5555

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.454

Organization unit

Faculty of Medicine

UT WoS

000253375100010

Keywords (in Czech)

Akutní lymfoblastická leukemie; fúzní transkript; prognostická hodnota

Keywords in English

ACUTE LYMPHOBLASTIC-LEUKEMIA; FUSION TRANSCRIPTS; PROGNOSTIC VALUE

Abstract

ORIG CZ

V originále

Frequent quantitative monitoring of fusion transcripts is useful for reliably predicting hematological relapse in AML patients. Treatment for molecular relapse of AML can be successful.

In Czech

Častý kvantitativní monitoring fúzních transkriptů je užitečný pro věrohodnou predikci hematologického relapsů u pacientů s AML. Léčba molekulárního relapsu může být úspěšná.

Links

LC06024, research and development project

Name: Centrum Jaroslava Hájka pro teoretickou a aplikovanou statistiku

Investor: Ministry of Education, Youth and Sports of the CR, Jaroslav Hájek Center for Theoretical and Applied Statistics

Citovat

DOUBEK, Michael, Ivo PALÁSEK, Z. POSPÍŠIL, S. STRUNCOVÁ, Dana DVOŘÁKOVÁ, M. BORSKÝ, Martin KLABUSAY, Y. BRYCHTOVÁ, Marta KREJČÍ and Jiří MAYER. Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression. Annals of Hematology. Springer, 2008, vol. 87, No 1, p. S4, 1 pp. ISSN 0939-5555.

@article{822015,
   author = {Doubek, Michael and Palásek, Ivo and Pospíšil, Z. and Struncová, S. and Dvořáková, Dana and Borský, M. and Klabusay, Martin and Brychtová, Y. and Krejčí, Marta and Mayer, Jiří},
   article_number = {1},
   keywords = {ACUTE LYMPHOBLASTIC-LEUKEMIA; FUSION TRANSCRIPTS; PROGNOSTIC VALUE},
   language = {eng},
   issn = {0939-5555},
   journal = {Annals of Hematology},
   title = {Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.},
   volume = {87},
   year = {2008}
}

TY  - JOUR
ID  - 822015
AU  - Doubek, Michael - Palásek, Ivo - Pospíšil, Z. - Struncová, S. - Dvořáková, Dana - Borský, M. - Klabusay, Martin - Brychtová, Y. - Krejčí, Marta - Mayer, Jiří
PY  - 2008
TI  - Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.
JF  - Annals of Hematology
VL  - 87
IS  - 1
SP  - S4
EP  - S4
PB  - Springer
SN  - 09395555
KW  - ACUTE LYMPHOBLASTIC-LEUKEMIA
KW  - FUSION TRANSCRIPTS
KW  - PROGNOSTIC VALUE
N2  - Frequent quantitative monitoring of fusion transcripts is useful for reliably predicting hematological relapse in AML patients. Treatment for molecular relapse of AML can be successful.
ER  -

DOUBEK, Michael, Ivo PALÁSEK, Z. POSPÍŠIL, S. STRUNCOVÁ, Dana DVOŘÁKOVÁ, M. BORSKÝ, Martin KLABUSAY, Y. BRYCHTOVÁ, Marta KREJČÍ and Jiří MAYER. Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression. \textit{Annals of Hematology}. Springer, 2008, vol.~87, No~1, p.~S4, 1 pp. ISSN~0939-5555.

Detailed Information on Publication Record