D 2009

Markers of oxidative stress in patients with acute heart failure following acute myocardial infarction

TOMANDL, Josef, Jiří PAŘENICA, Petr KALA, Martin POLOCZEK, Petr NEUGEBAUER et. al.

Basic information

Original name

Markers of oxidative stress in patients with acute heart failure following acute myocardial infarction

Name in Czech

Markey oxidativního stresu u pacientů s akutním srdečním selháním v průběhu akutního infarktu myokardu

Edition

Praha, Cor et Vasa - Supplementum, 1 pp. 2009

Publisher

Česká kardiologická společnost

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

ISSN

Keywords in English

oxidative stress; acute myocardial infarction; acute heart failure; malondialdehyde

Tags

Reviewed
Změněno: 12/5/2009 10:18, doc. RNDr. Josef Tomandl, Ph.D.

Abstract

V originále

Oxidative stress and persistent inflammation are implicated in the progression of heart failure. The aim of the study was to investigate selected parameters of oxidative stress (malondialdehyde, vitamins A and E and tumor necrosis factor alpha) in patients with acute heart failure after acute myocardial infarction. Plasma values of vitamins were almost within reference interval. Levels of malondialdehyde and TNF alpha were elevated in 18 and 46 % patients on admission, respectively. Level of malondialdehyde correlated positively with TNF alpha and vitamin A and level of TNFalpha correlated negatively with vitamin E on admission. In contrast to these correlations, there were no significant relationships between measured parameters and LV ejection fraction.

In Czech

Studie se zabývala vybranými markery oxidativního stresu (malondiladehyd, vitaminy A a E a tumor nekrotizující faktor alfa)u pacientů s s akutním srdečním selháním v průběhu akutního infarktu myokardu.

Links

MSM0021622402, plan (intention)
Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases