URBANOVÁ, Jana, Přemysl LUBAL, Iva SLANINOVÁ, Eva TÁBORSKÁ and Petr TÁBORSKÝ. Fluorescence properties of selected benzo[c]phenantridine and studies of their interaction with CT DNA. Analytical and Bioanalytical Chemistry. Heidelberg: Springer-Verlag GmbH, 2009, vol. 349, No 4, p. 997-1002. ISSN 1618-2642.
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Basic information
Original name Fluorescence properties of selected benzo[c]phenantridine and studies of their interaction with CT DNA
Name in Czech Fluorescenční vlastnosti vybraných benzofenantridinových alkaloidů a studium jejich interakcí s CT DNA
Authors URBANOVÁ, Jana (203 Czech Republic), Přemysl LUBAL (203 Czech Republic), Iva SLANINOVÁ (203 Czech Republic), Eva TÁBORSKÁ (203 Czech Republic) and Petr TÁBORSKÝ (203 Czech Republic, guarantor).
Edition Analytical and Bioanalytical Chemistry, Heidelberg, Springer-Verlag GmbH, 2009, 1618-2642.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.480
RIV identification code RIV/00216224:14310/09:00029331
Organization unit Faculty of Science
UT WoS 000266160400010
Keywords (in Czech) Sanguinarin Chelirubin Sanguirubin Chelilutin Makarpin
Keywords in English Sanguinarine Chelirubine Sanguirubine Chelilutine Macarpine
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Iva Slaninová, Ph.D., učo 2105. Changed: 12/3/2010 09:23.
Abstract
The spectral, especially fluorescence properties, of seven selected quaternary benzo[c]phenantridine alkaloids (sanguinarine, chelerythrine, chelirubine, sanguirubine, chelilutine, sanguilutine, and macarpine) were studied in presence and in absence of double-stranded DNA. This study has proved dramatic differences in fluorescence emission of all studied alkaloids in presence of calf thymus DNA in comparison to fluorescence of free alkaloids. The most remarkable are changes in emission spectra of macarpine, chelirubine, and sanguirubine. Association constants (logK) for interaction of all studied alkaloids with CT DNA were calculated.
Abstract (in Czech)
V článku jsou popsány fluorescenční vlastnosti vybraných alkaloidů (Sanguinarin, Chelirubin, Sanguirubin, Chelilutin, Makarpin, Chelerytrin), dále jsou uvedeny asociační konstanty interakce s CT DNA
Links
GA525/08/0819, research and development projectName: Rostlinné zdroje minoritních benzofenanthridinových alkaloidů a studium interakcí těchto alkaloidů s DNA
Investor: Czech Science Foundation, Plant sources of minor benzofenantridine alkaloids and study of heir interaction with DNA
LC06035, research and development projectName: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.
Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine
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