The aim of the article is to present the microregional managers‘ perception of space and regional development. These people together with other local leaders influence the future development of the area the most, and the interviewees have information and ideas from the leaders who are able to evaluate, objectively as well as subjectively, individual strategies and theories and their applicability for the area. During the research, the author of this article also tested the use of regional development theories inspired by the institutional economy on the area between Brno and Znojmo/Breclav.