J 2005

Outcome of patients with multiple myeloma and hypertension treated with angiotensin-I-converting enzyme inhibitors during high-dose chemotherapy.

BÜCHLER, Tomáš, Marta KREJČÍ, A. SVOBODNÍK, Zdeněk ADAM, J. MINAŘÍK et. al.

Basic information

Original name

Outcome of patients with multiple myeloma and hypertension treated with angiotensin-I-converting enzyme inhibitors during high-dose chemotherapy.

Name in Czech

Léčba hypertenze pomocí ACE-1 u pacientů s MM při vysokodávkované chemoterapii

Authors

BÜCHLER, Tomáš (703 Slovakia), Marta KREJČÍ (203 Czech Republic), A. SVOBODNÍK (203 Czech Republic), Zdeněk ADAM (203 Czech Republic), J. MINAŘÍK (203 Czech Republic), J. BAČOVSKÝ (203 Czech Republic), V. ŠČUDLA (203 Czech Republic), Jiří MAYER (203 Czech Republic), Jiří VORLÍČEK (203 Czech Republic) and Roman HÁJEK (203 Czech Republic, guarantor)

Edition

The hematology journal, England, Nature Publishing Group, 2005, 1466-4860

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/05:00035895

Organization unit

Faculty of Medicine

UT WoS

000227444300002

Keywords (in Czech)

mnohočetný myelom; hypertenze; ACE-1

Keywords in English

multiple myeloma; hypertension; angiotensin-1-converting enzyme
Změněno: 23/6/2009 10:13, Mgr. Anna Potáčová, Ph.D.

Abstract

V originále

In a retrospective study we have sought to determine whether the administration of angiotensin-I-converting enzyme inhibitors (ACEI) influences the outcome of patients with multiple myeloma (MM). Patients with MM who underwent autologous peripheral blood stem cell transplantation (PBSCT) (n=168) were studied. Patients taking ACEI alone or in combination with other antihypertensive agents during the hospital admission for PBSCT were allocated to the ACEI group (n=25; 15%). In conclusion, according to our findings, ACEI administered during PBSCT have adverse effect on survival of patients with MM.

In Czech

V publikaci je popsán vliv angiotenzin-1 konvertujícího enzymu na pacienty s MM po transplantaci.